运动康复改善冠状动脉微循环障碍的相关机制研究进展
Research Progress on the Mechanism of Exercise Rehabilitation in Improving Coronary Microcirculation Disorder
冠状动脉微循环障碍是指冠状前小动脉和小动脉结构和 / 或功能异常所致的临床综合征,与急性冠脉综合征、冠状动脉罪犯血管再通及心力衰竭等心血管疾病预后生存密切相关。作为心血管疾病预防和治疗的非药物干预手段,运动康复通过信号分子改善冠状动脉微循环障碍患者的内皮功能和氧化炎症刺激,恢复线粒体自噬水平,诱导血管周围脂肪组织功能恢复等。本文就运动康复干预冠状动脉微循环障碍的相关研究进展进行综述,旨在为运动康复治疗冠状动脉微循环障碍提供更多思路及参考。
oronary microcirculation disorder refers to the clinical syndrome caused by the abnormal structure and/or function of the precoronary arterioles and arterioleswhich is closely related to the prognosis of cardiovascular diseases such as acute coronary syndromecoronary offender vascular revascularization and heart failure.As a non-drug intervention for the prevention and treatment of cardiovascular diseasesexercise rehabilitation improves endothelial function and oxidative inflammation stimulation in patients with coronary microcirculation disorders through signaling moleculesrestores mitochondrial autophagy leveland induces functional recovery of perivascular adipose tissue.This article reviews the research progress of exercise rehabilitation intervention in coronary microcirculation disorderaiming to provide more ideas and references for exercise rehabilitation treatment of coronary microcirculation disorder.
孟怡、邓洁、高桂英、张世益、胡阳
内科学临床医学医学研究方法
冠状动脉微循环障碍运动康复内皮功能障碍线粒体自噬血管周围脂肪组织
孟怡,邓洁,高桂英,张世益,胡阳.运动康复改善冠状动脉微循环障碍的相关机制研究进展[EB/OL].(2025-01-15)[2025-08-05].https://chinaxiv.org/abs/202501.00173.点此复制
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