40~65 岁人群睡眠效率与血脂异常关联性研究

Background  Lipid metabolism of middle-aged and older adults may be influenced by decreased sleep efficiencybut their association still needs to be analyzed in-depth. Objective  To analyze the association between sleepefficiencySEand different lipid indexes in people aged 40-65and to explore the mediating role of central obesity in the association between SE and lipid to provide reference for exploring the pathway of dyslipidemia caused by SE and its prevention and treatment. Methods  From March to November 2022a face-to-face investigation was conducted in the physical examination center of Fuquan First People's Hospitallogistic regression was used to analyze the association between SE and lipid indexes and mediation model was used to analyze the mediating effect of WHR. Results  A total of 1095 subjects were included in this study and were divided into two groups according to the presence or absence of dyslipidemia. There were statistically significant differences in gendersmokingdrinkingexercisewaist circumferencehip circumference and waist-hip ratio between the two groupsP<0.05. After adjusting control variableshigher risk hypertriglyceridemia was observed in the group with low SE than high SE groupOR=1.3595%CI=1.03-1.77There was no statically significant association between SE and other lipid indexes. Mediation effect analysis showed that WHR had a partial mediating effect in the association between SE and hypertriglyceridemia=0.01995%CI=0.005-0.034WHR played a masking effect on the association between SE and Low high-density lipoproteinemia .Conclusion  Central Obesity may be an important pathway in the association between low SE and hypertriglyceridemia.