探究血管新生促进缺血性脑卒中运动功能恢复的机制
Exploring the Mechanism of Angiogenesis Promoting Motor Function Recovery in Ischemic Stroke
运动功能障碍是缺血性脑卒中(ischemic stroke,IS)患者主要表现,严重影响生活质量。血管新生通过改善脑组织血供,进而加速神经功能恢复,缓解运动功能障碍。本文综合探讨血管新生中起关键作用的血管生成因子,主要包括血管内皮生长因子 (vascular endothelial growth factor,VEGF)、血管生成素 (angiopoietins,Angs)、碱性成纤维细胞生长因子 (basic fibroblast growth factor,BFGF)和一氧化氮 (nitric oxide,NO) 等,为临床促进IS血管新生,促进运动功能恢复提供参考。
Motor dysfunction is the main manifestation of ischemic stroke (IS) patients, which seriously affects their quality of life. Tuina improves brain tissue blood supply by promoting angiogenesis, thereby accelerating neurological function recovery. This article comprehensively explores the mechanism by which tuina promotes angiogenesis, enhances neuroplasticity, inhibits inflammatory responses, and regulates cerebral hemodynamics by regulating signaling pathways such as VEGF and Ang-1/Tie-2. Provide reference for the recovery targets of IS motor function in clinical tuina.
于天源、秦丽娜、吕桃桃
神经病学、精神病学临床医学
缺血性脑卒中血管新生血管生成因子运动功能恢复
ischemic strokeangiogenesisangiogenic factorrecovery of motor function
于天源,秦丽娜,吕桃桃.探究血管新生促进缺血性脑卒中运动功能恢复的机制[EB/OL].(2025-02-26)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/202502-136.点此复制
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