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The genetics of an early Neolithic pastoralist from the Zagros, Iran

The genetics of an early Neolithic pastoralist from the Zagros, Iran

来源:bioRxiv_logobioRxiv
英文摘要

Abstract The agricultural transition profoundly changed human societies. We sequenced and analysed the first genome (1.39×) of an early Neolithic woman from Ganj Dareh, in the Zagros Mountains of Iran, a site with early evidence for an economy based on goat herding,ca. 10,000 BP. We show that Western Iran was inhabited by a population genetically most similar to hunter-gatherers from the Caucasus, but distinct from the Neolithic Anatolian people who later brought food production into Europe. The inhabitants of Ganj Dareh made little direct genetic contribution to modern European populations, suggesting they were somewhat isolated from other populations in the region. Runs of homozygosity are of a similar length to those from Neolithic Anatolians, and shorter than those of Caucasus and Western Hunter-Gatherers, suggesting that the inhabitants of Ganj Dareh did not undergo the large population bottleneck suffered by their northern neighbours. While some degree of cultural diffusion between Anatolia, Western Iran and other neighbouring regions is possible, the genetic dissimilarity of early Anatolian farmers and the inhabitants of Ganj Dareh supports a model in which Neolithic societies in these areas were distinct.

Beyer R.、Manica A.、Hofreiter M.、Jeon S.、Connell S.、Eriksson A.、Siska V.、Gamba C.、Merrett D. C.、Bhak J.、Pinhasi R.、Jones E. R.、Jeon Y.、Cho Y. S.、Gallego-Llorente M.、Meiklejohn C.

Department of Zoology, University of CambridgeDepartment of Zoology, University of CambridgeEvolutionary Adaptive Genomics, Institute for Biochemistry and Biology, Department of Mathematics and Natural Sciences, University of PotsdamThe Genomics Institute, Ulsan National Institute of Science and Technology (UNIST)||Department of Biomedical Engineering, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST)School of Archaeology and Earth Institute, University College DublinDepartment of Zoology, University of Cambridge||Integrative Systems Biology Laboratory, Division of Biological and Environmental Sciences & Engineering, King Abdullah University of Science and TechnologyDepartment of Zoology, University of CambridgeSchool of Archaeology and Earth Institute, University College Dublin||Smurfit Institute of Genetics, Trinity College Dublin||Centre for GeoGenetics, Natural History Museum of Denmark, University of CopenhagenDepartment of Archaeology, Simon Fraser UniversityThe Genomics Institute, Ulsan National Institute of Science and Technology (UNIST)School of Archaeology and Earth Institute, University College DublinDepartment of Zoology, University of CambridgeThe Genomics Institute, Ulsan National Institute of Science and Technology (UNIST)||Department of Biomedical Engineering, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST)The Genomics Institute, Ulsan National Institute of Science and Technology (UNIST)||Department of Biomedical Engineering, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST)Department of Zoology, University of CambridgeDepartment of Anthropology, University of Winnipeg

10.1101/059568

遗传学世界史生物科学研究方法、生物科学研究技术

Beyer R.,Manica A.,Hofreiter M.,Jeon S.,Connell S.,Eriksson A.,Siska V.,Gamba C.,Merrett D. C.,Bhak J.,Pinhasi R.,Jones E. R.,Jeon Y.,Cho Y. S.,Gallego-Llorente M.,Meiklejohn C..The genetics of an early Neolithic pastoralist from the Zagros, Iran[EB/OL].(2025-03-28)[2025-04-28].https://www.biorxiv.org/content/10.1101/059568.点此复制

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