Generation of novel SARS-CoV-2 variants on B.1.1.7 lineage in three patients with advanced HIV disease
Generation of novel SARS-CoV-2 variants on B.1.1.7 lineage in three patients with advanced HIV disease
ABSTRACT The emergence of new SARS-COV-2 variants is of public health concern in case of vaccine escape. Described are three patients with advanced HIV-1 and chronic SARS-CoV-2 infection in whom there is evidence of selection and persistence of novel mutations which are associated with increased transmissibility and immune escape.
Riddell Anna C.、Bible Jon、Owoyemi Dola、Pade Corinna、Cutino-Moguel Teresa、McKnight ¨￠ine、Storey Nathaniel、Gibbons Joseph M.、Harris Kathryn、Alexander Eliza、Murphy Maurice、Kele Beatrix、Harrington David、Dakshina Subathira
Virology Department, Division of Infection, Barts Health NHS TrustVirology Department, Division of Infection, Barts Health NHS TrustVirology Department, Division of Infection, Barts Health NHS TrustBlizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of LondonVirology Department, Division of Infection, Barts Health NHS TrustBlizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of LondonMicrobiology, Virology and Infection Prevention and Control, Great Ormond Street Hospital for Children NHS Foundation TrustBlizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of LondonVirology Department, Division of Infection, Barts Health NHS TrustVirology Department, Division of Infection, Barts Health NHS TrustDepartment of Infection and Immunity, Barts Health NHS TrustVirology Department, Division of Infection, Barts Health NHS TrustVirology Department, Division of Infection, Barts Health NHS TrustDepartment of Infection and Immunity, Barts Health NHS Trust
医学研究方法预防医学基础医学
Riddell Anna C.,Bible Jon,Owoyemi Dola,Pade Corinna,Cutino-Moguel Teresa,McKnight ¨￠ine,Storey Nathaniel,Gibbons Joseph M.,Harris Kathryn,Alexander Eliza,Murphy Maurice,Kele Beatrix,Harrington David,Dakshina Subathira.Generation of novel SARS-CoV-2 variants on B.1.1.7 lineage in three patients with advanced HIV disease[EB/OL].(2025-03-28)[2025-05-02].https://www.medrxiv.org/content/10.1101/2022.01.14.21267836.点此复制
评论