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首页|Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis

Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis

Clemons Nicholas J. Phillips Wayne A. Haupt Sue Fujihara Kenji M. Nijiagel Brunda Trapani Joe Stojanovski Diana Leimuehler Silke Zhang Bonnie Ang Ching-Seng Sutton Viv Jackson Thomas D. Simpson Kaylene J. Nikolic Iva

Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis

Clemons Nicholas J. 1Phillips Wayne A. 2Haupt Sue 1Fujihara Kenji M. 1Nijiagel Brunda 3Trapani Joe 1Stojanovski Diana 4Leimuehler Silke 5Zhang Bonnie 1Ang Ching-Seng 4Sutton Viv 1Jackson Thomas D. 4Simpson Kaylene J. 6Nikolic Iva6

作者信息

  • 1. Division of Cancer Research, Peter MacCallum Cancer Centre||Sir Peter MacCallum Department of Oncology, The University of Melbourne
  • 2. Division of Cancer Research, Peter MacCallum Cancer Centre||Sir Peter MacCallum Department of Oncology, The University of Melbourne||Department of Surgery, St. Vincent?ˉs Hospital
  • 3. Metabolomics
  • 4. Bio21 Institute of Biotechnology, The University of Melbourne
  • 5. Department for Molecular Enzymology, University of Potsdam
  • 6. Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre
  • 折叠

引用本文复制引用

Clemons Nicholas J.,Phillips Wayne A.,Haupt Sue,Fujihara Kenji M.,Nijiagel Brunda,Trapani Joe,Stojanovski Diana,Leimuehler Silke,Zhang Bonnie,Ang Ching-Seng,Sutton Viv,Jackson Thomas D.,Simpson Kaylene J.,Nikolic Iva.Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis[EB/OL].(2025-03-28)[2025-12-13].https://www.biorxiv.org/content/10.1101/2020.11.29.398867.

学科分类

肿瘤学/药学/分子生物学

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首发时间 2025-03-28
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