Molecular mechanisms behind global distribution of earthworm revealed by the genome
Molecular mechanisms behind global distribution of earthworm revealed by the genome
Abstract Earthworms (Annelida: Crassiclitellata), are widely distributed around the world due to their great adaptability. However, lack of a high-quality genome sequence prevents gaining the many insights into physiology, phylogeny, and genome evolution that could come from a good earthworm genome. Herein, we report a complete genome assembly of the earthworm Amynthas corticis of about 1.2 Gb, based on a strategy combining third-generation long-read sequencing and Hi-C mapping. A total of 29,256 protein-coding genes are annotated in this genome. Analysis of resequencing data indicates that this earthworm is a triploid species. Furthermore, gene family evolution analysis shows that comprehensive expansion of gene families in the earthworm genome has produced more defensive functions compared with other species in Annelida. Quantitative proteomic iTRAQ analysis shows 97 immune related proteins and 16S rDNA sequences shows 88 microbes with significantly response to pathogenic Escherichia coli O157:H7. Our genome assembly provides abundant and valuable resources for the earthworm research community, serving as a first step toward uncovering the mysteries of this species, may explain its powerful defensive functions adapt to complex environment and invasion from molecular level.
Zhang Yufeng、Kang Mingming、James Samuel W、Bi Yanmeng、Zhou Xin、Jiang Hao、Sun Zhenjun、Li Yuanbo、Zhao Yi、Zhang Yi、Yang Yang、Wang Xing
College of Biology, Langfang Normal UniversityCollege of Biological Sciences, China Agricultural UniversityMaharishi University of ManagementInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical CollegeCollege of Plant Protection, China Agricultural UniversityCollege of Resources and Environmental Sciences, China Agricultural UniversityCollege of Resources and Environmental Sciences, China Agricultural University||Beijing Key Laboratory of Biodiversity and Organic FarmingCollege of Resources and Environmental Sciences, China Agricultural University||Beijing Key Laboratory of Biodiversity and Organic FarmingCollege of Resources and Environmental Sciences, China Agricultural UniversitySchool of Environmental Science & Engineering, Southern University of Science and TechnologyBeijing Gencode Diagnostics LaboratoryCollege of Resources and Environmental Sciences, China Agricultural University||Beijing Key Laboratory of Biodiversity and Organic Farming
分子生物学动物学遗传学
Zhang Yufeng,Kang Mingming,James Samuel W,Bi Yanmeng,Zhou Xin,Jiang Hao,Sun Zhenjun,Li Yuanbo,Zhao Yi,Zhang Yi,Yang Yang,Wang Xing.Molecular mechanisms behind global distribution of earthworm revealed by the genome[EB/OL].(2025-03-28)[2025-07-01].https://www.biorxiv.org/content/10.1101/853267.点此复制
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