LIONS: Analysis Suite for Detecting and Quantifying Transposable Element Initiated Transcription from RNA-seq
LIONS: Analysis Suite for Detecting and Quantifying Transposable Element Initiated Transcription from RNA-seq
Abstract SummaryTransposable Elements (TEs) influence the evolution of novel transcriptional networks yet the specific and meaningful interpretation of how TE-initiation events contribute to the transcriptome has been marred by computational and methodological deficiencies. We developed LIONS for the analysis of paired-end RNA-seq data to specifically detect and quantify TE-initiated transcripts. AvailabilitySource code, container, test data and instruction manual are freely available at www.github.com/ababaian/LIONS. Contactababaian@bccrc.ca or mahdi.karimi@lms.mrc.ac.uk or dmager@bccrc.ca. Supplementary informationSupplementary data are available at Bioinformatics online.
Thompson Richard、Gagnier Liane、Mager Dixie L.、Karimi Mohammad M.、Babaian Artem、Lever Jake
Qatar Biomedical Research Institute, Hamad Bin Khalifa UniversityTerry Fox Laboratory, BC CancerTerry Fox Laboratory, BC Cancer||University of British ColumbiaMRC London Institute of Medical Sciences, Imperial CollegeTerry Fox Laboratory, BC Cancer||University of British ColumbiaUniversity of British Columbia||Michael Smith Genome Sciences Centre, BC Cancer
遗传学分子生物学生物科学研究方法、生物科学研究技术
Thompson Richard,Gagnier Liane,Mager Dixie L.,Karimi Mohammad M.,Babaian Artem,Lever Jake.LIONS: Analysis Suite for Detecting and Quantifying Transposable Element Initiated Transcription from RNA-seq[EB/OL].(2025-03-28)[2025-06-19].https://www.biorxiv.org/content/10.1101/149864.点此复制
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