Random burst sensing of neurotransmitters
Random burst sensing of neurotransmitters
Abstract We introduce a random sensing approach to neurotransmitter detection that provides concurrent, co-localized detection of dopamine, serotonin, norepinephrine and pH. The approach generates high quality out-of-sample predictions at 10 milliseconds per estimate. Similar high-quality estimates result when the data are down-sampled suggesting that even more dramatic speedups are possible. The method also works using electrophysiological probes in routine use in clinical preparations thus transforming these and similar electrodes into ultra-fast sources of multi-transmitter information.
Montague P. Read、Moran Rosalyn J、Lohrenz Terry、Kishida Kenneth T.、White Jason
Fralin Biomedical Research Institute, Virginia Tech||Dept Physics, Virginia Tech||Wellcome Centre for Human Neuroimaging, University College LondonDepartment of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King?ˉs College LondonFralin Biomedical Research Institute, Virginia TechDepartment of Physiology and Pharmacology, Wake Forest School of Medicine||Department of Neurosurgery, Wake Forest School of MedicineFralin Biomedical Research Institute, Virginia Tech
神经病学、精神病学基础医学生物科学研究方法、生物科学研究技术
Montague P. Read,Moran Rosalyn J,Lohrenz Terry,Kishida Kenneth T.,White Jason.Random burst sensing of neurotransmitters[EB/OL].(2025-03-28)[2025-05-06].https://www.biorxiv.org/content/10.1101/607077.点此复制
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