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Antibody Responses to 3 rd Dose mRNA Vaccines in Nursing Home and Assisted Living Residents

Antibody Responses to 3 rd Dose mRNA Vaccines in Nursing Home and Assisted Living Residents

来源:medRxiv_logomedRxiv
英文摘要

Abstract A comparison of SARS-CoV-2 wild-type and the beta variant virus neutralization capacity between 2 and 3 mRNA vaccine series in nursing home residents, and between nursing home and assisted living residents strongly supports 3rd dose vaccine recommendations, and equivalent polices for nursing homes and assisted living settings. Findings suggest that residents mount a robust humoral response to a 3rd mRNA vaccination, and have greater neuralization capacity compared to a 2 dose series.

Zhang Ali、Breznik Jessica A.、Miller Matthew S.、Bowdish Dawn M. E.、Costa Andrew P.、Nazy Ishac、Clare Rumi

McMaster Immunology Research Centre, McMaster University||Michael G. DeGroote Institute for Infectious Disease Research, McMaster University||Department of Biochemistry & Biomedical Sciences, McMaster UniversityMcMaster Immunology Research Centre, McMaster University||Michael G. DeGroote Institute for Infectious Disease Research, McMaster University||Department of Medicine, Michael G. DeGroote School of Medicine, McMaster UniversityMcMaster Immunology Research Centre, McMaster University||Michael G. DeGroote Institute for Infectious Disease Research, McMaster University||Department of Biochemistry & Biomedical Sciences, McMaster UniversityMcMaster Immunology Research Centre, McMaster University||Michael G. DeGroote Institute for Infectious Disease Research, McMaster University||Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University||Firestone Institute of Respiratory Health, St Joseph?ˉs HealthcareDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University||Department of Health Research Methods, Evidence, and Impact, McMaster University||Centre for Integrated Care, St. Joseph?ˉs Health SystemDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University||McMaster Centre for Transfusion Research, McMaster UniversityDepartment of Medicine, Michael G. DeGroote School of Medicine, McMaster University

10.1101/2021.12.17.21267996

预防医学医学研究方法基础医学

Zhang Ali,Breznik Jessica A.,Miller Matthew S.,Bowdish Dawn M. E.,Costa Andrew P.,Nazy Ishac,Clare Rumi.Antibody Responses to 3 rd Dose mRNA Vaccines in Nursing Home and Assisted Living Residents[EB/OL].(2025-03-28)[2025-06-23].https://www.medrxiv.org/content/10.1101/2021.12.17.21267996.点此复制

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