24周太极拳运动对中老年人NKT细胞及其分泌细胞因子的影响
he effect of 24 weeks Taichi exercise on NKT cells secrete cytokines in the elderly
目的:观察24周太极拳锻炼对中老年人外周血中NKT细胞及其分泌细胞因子格局的影响,探究太极拳改善中老年人免疫机能的调节机制。方法:20名健康中老年女性随机分为对照组和实验组,每组10人。其中实验组进行为期24周的太极拳锻炼,实验前后采用流式细胞术检测外周血中NKT细胞数量的表达,并通过体外观测NKT增殖能力的变化及其分泌细胞因子IFN-?、IL-4的变化。结果:24周太极拳运动后,实验组NKT细胞数量及增殖能力显著性升高,增殖后IFN-?、IL-4的表达量均显著性升高,其中IFN-?升高幅度较大。结论:NKT细胞数量及增殖能力的改变导致IFN-?、IL-4表达量的改变可能是太极拳免疫调节机制中的一条重要路径。
Object: This essay aims to research the regulation mechanism of that Taijiquan how to improve immunodeficiency of the middle age and the old, by observing the influence on their blood of the factor pattern of NKT cells and its Secreting cells with 24weeks Taijiquan practice. Methods: Dividing 170 healthy the middle age and the old into two group randomly:the control group and the experimental group,the later group had 24 weeks Taijiquan practice. To test the expression of the NKT cell quantity of blood by Flow cytometry, to observe the change of cell activity of NKT cells and its Secreting cells factor IFN-?、IL-4 with proliferation. Results: It has a raise of the NKT cell quantity and the activity of the experimental group significantly,and so the expression quantity of IFN-?、IL-4 did after proliferation,the original factor pattern of cell has no change. Conclusion :It may be a important path for regulation mechanism of that Taijiquan how to improve immunodeficiency that the change of NKT cell quantity and the activity cause the secretion pattern's change of IFN-γ、IL-4.
赵影、虞定海
医药卫生理论中医学基础医学
民族传统体育太极拳NKT增殖细胞因子
raditional sportsTaijiquanNKTproliferationcell factor
赵影,虞定海.24周太极拳运动对中老年人NKT细胞及其分泌细胞因子的影响[EB/OL].(2011-07-04)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201107-10.点此复制
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