Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study
Abstract BackgroundHealthcare workers (HCW) are at increased risk of being infected with SARS-CoV-2, yet limited information is available on risk factors of infection. MethodsWe pooled data on occupational surveillance of 10,654 HCW who were tested for SARS-CoV-2 infection in six Italian centers. Information was available on demographics, job title, department of employment, source of exposure, use of personal protective equipment (PPE), and COVID-19-related symptoms. We fitted multivariable logistic regression models to calculate odds ratios (OR) and 95% confidence intervals (CI). FindingsThe prevalence of infection varied across centers and ranged from 3.0% to 22.0%, being strongly correlated with that of the respective areas. Women were at lower risk of infection compared to men. Fever, cough, dyspnea and malaise were the symptoms most strongly associated with infection, together with anosmia and ageusia. No differences in the risk of infection were detected between job titles, or working in a COVID-19 designated department. Reported contact with a patient inside or outside the workplace was a risk factor. Use of a mask was strongly protective against risk of infection as was use of gloves. The use of a mask by the source of exposure (patient or colleague) had an independent effect in reducing infection risk.
Working Group on SARS-CoV-2 infection in Italian healthcare workers.、Boffetta Paolo、Palma Giuseppe De、Pira Enrico、Sala Emma、Tafuri Silvio、Apostoli Pietro、Vimercati Luigi、Durando Paolo、Coggiola Maurizio、Gattini Vittorio、Cristaudo Alfonso、Violante Francesco、Spatari Giovanna、Icardi Giancarlo
Stony Brook Cancer Center, Stony Brook University||Department of Medical and Surgical Sciences, University of BolognaDepartment of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of BresciaDepartment of Public Health and Pediatric Sciences, University of TurinUniversity Hospital Spedali Civili di BresciaInterdisciplinary Department of Medicine, University of BariDepartment of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia||Italian Society of Occupational MedicineInterdisciplinary Department of Medicine, University of BariDepartment of Health Sciences, University of Genoa||IRCCS Ospedale Policlinico San MartinoUniversity Hospital City of Health and Science of TurinUniversity Hospital Pisana, Pisa||University of, PisaUniversity Hospital Pisana, Pisa||University of, PisaDepartment of Medical and Surgical Sciences, University of BolognaDepartment of Biomedical and Dentistry Sciences and Morphological and Functional Imaging, University of MessinaDepartment of Health Sciences, University of Genoa||IRCCS Ospedale Policlinico San Martino
医学研究方法预防医学医药卫生理论
Working Group on SARS-CoV-2 infection in Italian healthcare workers.,Boffetta Paolo,Palma Giuseppe De,Pira Enrico,Sala Emma,Tafuri Silvio,Apostoli Pietro,Vimercati Luigi,Durando Paolo,Coggiola Maurizio,Gattini Vittorio,Cristaudo Alfonso,Violante Francesco,Spatari Giovanna,Icardi Giancarlo.Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study[EB/OL].(2025-03-28)[2025-08-02].https://www.medrxiv.org/content/10.1101/2020.07.29.20158717.点此复制
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