DAnIEL: A User-Friendly Web Server for Fungal ITS Amplicon Sequencing Data
DAnIEL: A User-Friendly Web Server for Fungal ITS Amplicon Sequencing Data
Abstract Trillions of microbes representing all kingdoms of life are resident in, and on, humans holding essential roles for host development and physiology. The last decade over a dozen online tools and servers, accessible via public domain, have been developed for the analysis of bacterial sequences, however, the analysis of fungi is still in its infancy. Here we present a web server dedicated to the comprehensive analysis of the human mycobiome for (i) translating raw sequencing reads to data tables and high-standard figures; (ii) integrating statistical analysis and machine learning with a manually curated relational database; (iii) comparing the user’s uploaded datasets with publicly available from the Sequence Read Archive. Using 2,048 publicly available ITS samples, we demonstrated the utility of DAnIEL web server on large scale datasets and show the differences in fungal communities between human gut, skin, nasopharynx, and oral body sites.
Beemelmanns Christine、Kurzai Oliver、Loos Daniel、Zhang Lu、Panagiotou Gianni
Chemical Biology of Microbe-Host Interactions, Leibniz Institute for Natural Product Research and Infection BiologyInstitute for Hygiene and Microbiology, University of W¨1rzburgSystems Biology and Bioinformatics, Leibniz Institute for Natural Product Research and Infection BiologySystems Biology and Bioinformatics, Leibniz Institute for Natural Product Research and Infection BiologySystems Biology and Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology||Systems Biology and Bioinformatics, School of Biological Sciences, Faculty of Science, The University of Hong Kong
微生物学生物科学研究方法、生物科学研究技术基础医学
Beemelmanns Christine,Kurzai Oliver,Loos Daniel,Zhang Lu,Panagiotou Gianni.DAnIEL: A User-Friendly Web Server for Fungal ITS Amplicon Sequencing Data[EB/OL].(2025-03-28)[2025-04-29].https://www.biorxiv.org/content/10.1101/2021.04.12.437814.点此复制
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