Ventrointermediate thalamic stimulation improves motor learning in humans
Ventrointermediate thalamic stimulation improves motor learning in humans
Ventrointermediate thalamic stimulation (VIM-DBS) modulates oscillatory activity in a cortical network including primary motor cortex, premotor cortex, and parietal cortex. Here we show that, beyond the beneficial effects of VIM-DBS on motor execution, this form of invasive stimulation facilitates production of sequential finger movements that follow a fixed sequence but not when the sequence is selected at random. These results highlight the role of thalamo-cortical activity in motor learning.
Galazky Imke、Hinrichs Hermann、Nasuto Slawomir J.、de Oliveira Andrade Adriano、Knight Robert T.、Ivry Richard B.、Buentjen Lars、Sweeney-Reed Catherine M.、Terzic Laila、Voegtle Angela、Voges J¨1rgen、Hartong Nanna、Farahat Amr、Deliano Matthias
基础医学神经病学、精神病学生理学
Galazky Imke,Hinrichs Hermann,Nasuto Slawomir J.,de Oliveira Andrade Adriano,Knight Robert T.,Ivry Richard B.,Buentjen Lars,Sweeney-Reed Catherine M.,Terzic Laila,Voegtle Angela,Voges J¨1rgen,Hartong Nanna,Farahat Amr,Deliano Matthias.Ventrointermediate thalamic stimulation improves motor learning in humans[EB/OL].(2025-03-28)[2025-05-16].https://www.biorxiv.org/content/10.1101/2023.09.19.558378.点此复制
评论