Pre-pandemic mental health and disruptions to healthcare, economic, and housing outcomes during COVID –19: evidence from 12 UK longitudinal studies
Pre-pandemic mental health and disruptions to healthcare, economic, and housing outcomes during COVID –19: evidence from 12 UK longitudinal studies
Abstract BackgroundThe COVID-19 pandemic and associated virus suppression measures have disrupted lives and livelihoods and people already experiencing mental ill-health may have been especially vulnerable. AimTo quantify mental health inequalities in disruptions to healthcare, economic activity and housing. Method59,482 participants in 12 UK longitudinal adult population studies with data collected prior to and during the COVID-19 pandemic. Within each study we estimated the association between psychological distress assessed pre-pandemic and disruptions since the start of the pandemic to three domains: healthcare (medication access, procedures, or appointments); economic activity (employment, income, or working hours); and housing (change of address or household composition). Meta-analyses were used to pool estimates across studies. ResultsAcross the analysed datasets, one to two-thirds of participants experienced at least one disruption, with 2.3-33.2% experiencing disruptions in two or more domains. One standard deviation higher pre-pandemic psychological distress was associated with: (i) increased odds of any healthcare disruptions (OR=1.30; [95% CI:1.20–1.40]) with fully adjusted ORs ranging from 1.24 [1.09–1.41] for disruption to procedures and 1.33 [1.20– 1.49] for disruptions to prescriptions or medication access; (ii) loss of employment (OR=1.13 [1.06–1.21]) and income (OR=1.12 [1.06 –1.19]) and reductions in working hours/furlough (OR=1.05 [1.00–1.09]); (iii) no associations with housing disruptions (OR=1.00 [0.97–1.03]); and (iv) increased likelihood of experiencing a disruption in at least two domains (OR=1.25 [1.18–1.32]) or in one domain (OR=1.11 [1.07–1.16]) relative to no disruption. ConclusionPeople experiencing psychological distress pre-pandemic have been more likely to experience healthcare and economic disruptions, and clusters of disruptions across multiple domains during the pandemic. Failing to address these disruptions risks further widening the existing inequalities in mental health.
Griffith Gareth J.、Fitzsimons Emla、Silverwood Richard J.、Chaturvedi Nish、Steves Claire J.、Steptoe Andrew、Davies Helena L.、Kwong Alex S.F.、McElroy Eoin、Gessa Giorgio Di、Thompson Ellen J.、Ploubidis George B.、Niedzwiedz Claire L.、Green Michael J.、Porteous David J、Mundy Jessica、Maddock Jane、Katikireddi Srinivasa Vittal、Breen Gerome、Patalay Praveetha、Stevenson Anna J.、Henderson Morag
MRC Integrative Epidemiology Unit, University of BristolCentre for Longitudinal Studies, UCL Social Research Institute, University College LondonCentre for Longitudinal Studies, UCL Social Research Institute, University College LondonMRC Unit for Lifelong Health and Ageing, University College LondonDepartment of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King?ˉs College LondonInstitute of Epidemiology and Health Care, University College LondonSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King?ˉs College LondonDivision of Psychiatry, University of Edinburgh||MRC Integrative Epidemiology Unit, University of BristolDepartment of Neuroscience, Psychology and Behaviour, University of LeicesterInstitute of Epidemiology and Health Care, University College LondonDepartment of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King?ˉs College LondonCentre for Longitudinal Studies, UCL Social Research Institute, University College LondonInstitute of Health & Wellbeing, University of GlasgowMRC/CSO Social & Public Health Sciences Unit, University of GlasgowCentre for Genomic and Experimental Medicine, University of EdinburghSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King?ˉs College LondonMRC Unit for Lifelong Health and Ageing, University College LondonMRC/CSO Social & Public Health Sciences Unit, University of GlasgowSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King?ˉs College London||Maudsley Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust and King?ˉs College LondonMRC Unit for Lifelong Health and Ageing, University College London||Centre for Longitudinal Studies, UCL Social Research Institute, University College LondonCentre for Genomic and Experimental Medicine, University of EdinburghCentre for Longitudinal Studies, UCL Social Research Institute, University College London
医药卫生理论医学研究方法
Griffith Gareth J.,Fitzsimons Emla,Silverwood Richard J.,Chaturvedi Nish,Steves Claire J.,Steptoe Andrew,Davies Helena L.,Kwong Alex S.F.,McElroy Eoin,Gessa Giorgio Di,Thompson Ellen J.,Ploubidis George B.,Niedzwiedz Claire L.,Green Michael J.,Porteous David J,Mundy Jessica,Maddock Jane,Katikireddi Srinivasa Vittal,Breen Gerome,Patalay Praveetha,Stevenson Anna J.,Henderson Morag.Pre-pandemic mental health and disruptions to healthcare, economic, and housing outcomes during COVID –19: evidence from 12 UK longitudinal studies[EB/OL].(2025-03-28)[2025-08-26].https://www.medrxiv.org/content/10.1101/2021.04.01.21254765.点此复制
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