Aligning sequence from molecular inversion probes
Aligning sequence from molecular inversion probes
ABSTRACT SummaryMolecular inversion probes (MIP’s) allow efficient enrichment of genomic regions of interest for the purpose of targeted sequencing. To date, there is a paucity of simple-to-use software to align sequences derived from this method. Here, we describe a single program that performs mapping, arm removal, and deduplication before outputting alignments in SAM format. Availabilitybwa-mips is available at https://github.com/brentp/bwa-mips under the MIT license. Contactbpederse@gmail.com
Pedersen Brent S.、Murphy Elissa、Schwartz David A.、Yang Ivana V.
Department of Medicine, University of Colorado Denver, School of MedicineDepartment of Medicine, University of Colorado Denver, School of MedicineDepartment of Medicine, University of Colorado Denver, School of MedicineDepartment of Medicine, University of Colorado Denver, School of Medicine
分子生物学生物科学研究方法、生物科学研究技术计算技术、计算机技术
Pedersen Brent S.,Murphy Elissa,Schwartz David A.,Yang Ivana V..Aligning sequence from molecular inversion probes[EB/OL].(2025-03-28)[2025-08-02].https://www.biorxiv.org/content/10.1101/007260.点此复制
评论