Aberrant motor contagion of emotions in psychopathy and high-functioning autism
Aberrant motor contagion of emotions in psychopathy and high-functioning autism
Abstract Psychopathy and autism are both associated with aberrant social interaction and communication, yet only psychopaths are markedly antisocial and violent. Here we compared the functional neural alterations underlying these two different phenotypes with distinct patterns of socioemotional difficulties. We studied 19 incarcerated male offenders with high psychopathic traits, 20 males with high-functioning autism and 19 age-matched healthy controls. All groups underwent functional magnetic resonance imaging while they viewed dynamic happy, angry and disgust facial expressions or listened to laughter and crying sounds. Psychopathy was associated with reduced somatomotor responses to almost all expressions, while subjects with autism demonstrated less marked and emotion-specific alterations in the somatomotor area. These data suggest that psychopathy and autism involve both common and distinct functional alterations in the brain networks involved in socioemotional processing.
Noppari Tuomo、Hudson Matthew、Venetjoki M. Niina、Lauerma Hannu、Tiihonen Jari、Putkinen Vesa、Sun Lihua、Nummenmaa Lauri、Tani Pekka、Nazari-Farsani Sanaz、Lindberg Nina、Lukkarinen Lasse、Karlsson Henry K.、Hirvonen Jussi、Sepp?l? Kerttu、Salomaa Marja
Department of Psychiatry, Helsinki University HospitalTurku PET Centre, University of TurkuPsychiatric Hospital for Prisoners, Health Care Services for PrisonersPsychiatric Hospital for Prisoners, Health Care Services for PrisonersDepartment of Clinical Neuroscience, Karolinska Institute and Center for Psychiatry Research, Stockholm City Council||Department of Forensic Psychiatry, University of Eastern FinlandTurku PET Centre, University of TurkuTurku PET Centre, University of TurkuTurku PET Centre, University of Turku||Department of Psychology, University of TurkuDepartment of Psychiatry, Helsinki University HospitalTurku PET Centre, University of TurkuDepartment of Forensic Psychiatry, Helsinki University Hospital, University of HelsinkiTurku PET Centre, University of TurkuTurku PET Centre, University of TurkuTurku PET Centre, University of Turku||Department of Radiology, Turku University HospitalTurku PET Centre, University of TurkuPsychiatric Hospital for Prisoners, Health Care Services for Prisoners
神经病学、精神病学基础医学生理学
Noppari Tuomo,Hudson Matthew,Venetjoki M. Niina,Lauerma Hannu,Tiihonen Jari,Putkinen Vesa,Sun Lihua,Nummenmaa Lauri,Tani Pekka,Nazari-Farsani Sanaz,Lindberg Nina,Lukkarinen Lasse,Karlsson Henry K.,Hirvonen Jussi,Sepp?l? Kerttu,Salomaa Marja.Aberrant motor contagion of emotions in psychopathy and high-functioning autism[EB/OL].(2025-03-28)[2025-04-27].https://www.biorxiv.org/content/10.1101/2021.07.05.450842.点此复制
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