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ENLIGHT Consensus Checklist and Guidelines for reporting laboratory studies on the non-visual effects of light in humans

ENLIGHT Consensus Checklist and Guidelines for reporting laboratory studies on the non-visual effects of light in humans

来源:bioRxiv_logobioRxiv
英文摘要

Abstract Beyond vision, light has wide-reaching effects on human health and well-being. However, there is no consensus on reporting light characteristics in studies investigating non-visual responses to light. This project aimed at developing a reporting checklist for laboratory-based investigations on the impact of light on non-visual physiology. To this end, a four-step modified Delphi process (three questionnaire-based feedback rounds and one face-to-face group discussion) involving international experts was conducted. Across these four rounds, an initial list of 61 items related to reporting light-based interventions was condensed to a final checklist containing 25 items, based upon consensus among experts (final n=60). Nine of these items were determined to be necessary to report regardless of the specific research question or context. A description of each item was provided in the accompanying guidelines. Most participants (92%) reported being satisfied or very satisfied with the consensus process, checklist, and guidelines. The ENLIGHT Checklist and Guidelines are the first consensus-based guidelines for documenting and reporting ocular light-based interventions for human studies. The implementation of the checklist and guidelines will enhance the impact of light-based research by ensuring comprehensive documentation and reproducibility and enabling data aggregation across studies.

the ENLIGHT Consortium、Najjar Raymond P.、Spitschan Manuel、Lok Renske、McGlashan Elise、Kervezee Laura

Department of Ophthalmology, National University of Singapore||Center for Innovation & Precision Eye Health, National University of Singapore||Singapore Eye Research Institute||Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Medical SchoolTUM School of Medicine & Health, Department of Health and Sport Sciences, Technical University of Munich||TUM Institute for Advanced Study (TUM-IAS), Technical University of Munich||Max Planck Institute for Biological Cybernetics, Max Planck Research Group Translational Sensory & Circadian NeuroscienceDepartment of Psychiatry and Behavioral Sciences, Stanford UniversitySchool of Psychological Science and Turner Institute for Brain and Mental Health, Monash UniversityLaboratory for Neurophysiology, Department of Cellular and Chemical Biology, Leiden University Medical Center

10.1101/2023.03.17.532785

医学研究方法生理学生物科学研究方法、生物科学研究技术

the ENLIGHT Consortium,Najjar Raymond P.,Spitschan Manuel,Lok Renske,McGlashan Elise,Kervezee Laura.ENLIGHT Consensus Checklist and Guidelines for reporting laboratory studies on the non-visual effects of light in humans[EB/OL].(2025-03-28)[2025-08-23].https://www.biorxiv.org/content/10.1101/2023.03.17.532785.点此复制

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