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Compositional Cyber-Physical Epidemiology of COVID-19

Compositional Cyber-Physical Epidemiology of COVID-19

来源:medRxiv_logomedRxiv
英文摘要

Abstract COVID-19 pandemic has posed significant challenges globally. Countries have adopted different strategies with varying degrees of success. Epidemiologists are studying the impact of government actions using scenario analysis. However, the interactions between the government policy and the disease dynamics are not formally captured. We, for the first time, formally study the interaction between the disease dynamics, which is modelled as a physical process, and the government policy, which is modelled as the adjoining controller. Our approach enables compositionality, where either the plant or the controller could be replaced by an alternative model. Our work is inspired by the engineering approach for the design of Cyber-Physical Systems (CPSs). Consequently, we term the new framework Compositional Cyber-Physical Epidemiology (CCPE). We created different classes of controllers and applied these to control the disease in New Zealand and Italy. Our controllers closely follow government decisions based on their published data. We not only reproduce the pandemic progression faithfully in New Zealand and Italy but also show the tradeoffs produced by differing control actions.

Ro Jin Woo、Ai Weiwei、Prasad Debi、Allen Nathan、Roop Partha S.

Department of Electrical, Computer and Software Engineering, University of AucklandDepartment of Electrical, Computer and Software Engineering, University of AucklandFaculty of Medical and Health Sciences, University of AucklandDepartment of Electrical, Computer and Software Engineering, University of AucklandDepartment of Electrical, Computer and Software Engineering, University of Auckland

10.1101/2020.04.26.20081125

医药卫生理论医学研究方法自动化技术、自动化技术设备

Ro Jin Woo,Ai Weiwei,Prasad Debi,Allen Nathan,Roop Partha S..Compositional Cyber-Physical Epidemiology of COVID-19[EB/OL].(2025-03-28)[2025-04-29].https://www.medrxiv.org/content/10.1101/2020.04.26.20081125.点此复制

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