OncoCTMiner: streamlining precision oncology trial matching via molecular profile analysis
OncoCTMiner: streamlining precision oncology trial matching via molecular profile analysis
Abstract SummaryOncoCTMiner is an innovative platform that streamlines precision oncology trial matching by integrating genetic profile analysis and clinical data. It utilizes manual tagging and automated entity recognition to identify six major biomedical concepts within clinical trial records. The platform currently contains a database of over 457,000 clinical trials, enabling quick and advanced search functionalities. Additionally, OncoCTMiner features an automated matching system based on genetic profiles and clinical data, providing real-time matching reports for suitable clinical trials. This platform aims to enhance patient enrollment in precision oncology trials, facilitating the development of personalized cancer therapies. Availability and ImplementationOncoCTMiner is available at https://oncoctminer.chosenmedinfo.com. Contactniubf@cnic.cn or qimingzhou@chosenmedtech.com Supplementary informationSupplementary data are available at medRxiv online. Graphic Abstractmedrxiv;2023.07.10.23292477v1/UFIG1F1ufig1Graphic abstract:A) OncoCTMiner’s role in precision oncology trial enrollment. B) OncoCTMiner takes clinical and genetic profiles as inputs and utilizes a trial matching and filtering system to generate a report of matched trials. C) Strategy for building the clinical trial eligibility criteria database. D) Automatic matching strategy for genomics-driven oncology trials.
Huang Xiaoqian、Zhai JinCheng、Li Feihong、Zhou Qiming、Liu Yueyue、Xu Quan、Li Yang、Sun Dawei、Niu Beifang
Beijing ChosenMed Clinical Laboratory Co. Ltd., Jinghai Industrial Park, Economic and Technological Development AreaBeijing ChosenMed Clinical Laboratory Co. Ltd., Jinghai Industrial Park, Economic and Technological Development AreaBeijing ChosenMed Clinical Laboratory Co. Ltd., Jinghai Industrial Park, Economic and Technological Development AreaBeijing ChosenMed Clinical Laboratory Co. Ltd., Jinghai Industrial Park, Economic and Technological Development Area||ChosenMed Technology (Zhejiang) Co. Ltd.Beijing ChosenMed Clinical Laboratory Co. Ltd., Jinghai Industrial Park, Economic and Technological Development AreaBeijing ChosenMed Clinical Laboratory Co. Ltd., Jinghai Industrial Park, Economic and Technological Development Area||ChosenMed Technology (Zhejiang) Co. Ltd.Chongqing Research Institute of Big Data, Peking UniversityBeijing ChosenMed Clinical Laboratory Co. Ltd., Jinghai Industrial Park, Economic and Technological Development Area||ChosenMed Technology (Zhejiang) Co. Ltd.ChosenMed Technology (Zhejiang) Co. Ltd.||Computer Network Information Center, Chinese Academy of Sciences||University of Chinese Academy of Sciences
肿瘤学医学研究方法生物科学研究方法、生物科学研究技术
Huang Xiaoqian,Zhai JinCheng,Li Feihong,Zhou Qiming,Liu Yueyue,Xu Quan,Li Yang,Sun Dawei,Niu Beifang.OncoCTMiner: streamlining precision oncology trial matching via molecular profile analysis[EB/OL].(2025-03-28)[2025-06-16].https://www.medrxiv.org/content/10.1101/2023.07.10.23292477.点此复制
评论