高住低训对大鼠体重和骨骼肌形态学影响

In this paper the effect of endurance exercise and living high training low (HiLo) on body weight and muscle mass, Fiber cross-sectional areas of skeletal muscle in rats were studied in order to research regular of the effect of hypoxia and exercise on growth of skeletal muscle. Methods: SD rats were randomly divided into four groups: normoxia control group, normoxic exercise group, hypoxic exposure group, living high training low (HiLo) group. Body weight and muscle mass, Fiber cross-sectional areas of skeletal muscle were tested in all groups of rats. Results:（1）After 28 days, the HiLo group rats body weight had been decreased significantly;（2）After 28 days, muscle mass decreased significantly in the normoxic exercise group, hypoxic exposure group, HiLo group group (p<0.05);（3）After 28 days, the mean cross-sectional areas of skeletal muscle in hypoxic exposure group were lower than the Control significantly; Conclusions: HiLo restrained skeletal muscle growth of rats, and may have the negative effect on capacity of exercise in skeletal muscle.