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Enhanced envelope coding following acoustic trauma is detrimental to neural coding of speech in noise

Enhanced envelope coding following acoustic trauma is detrimental to neural coding of speech in noise

来源:bioRxiv_logobioRxiv
英文摘要

Abstract People with hearing loss struggle understanding speech in noisy backgrounds. Speech-intelligibility models highlight the importance of slow-varying envelopes of speech and noise; however, the physiological basis of impaired perception remains unclear. We provide neurophysiological evidence that, although acoustic trauma enhances both speech and noise envelopes, disruptions in cochlear tonotopicity preferentially enhance neural responses to noise in noisy speech. These results provide mechanistic insights into everyday-communication challenges created by hearing loss.

Heinz Michael G.、Parida Satyabrata

Department of Speech, Language, and Hearing Sciences, Purdue University||Weldon School of Biomedical Engineering, Purdue UniversityDepartment of Speech, Language, and Hearing Sciences, Purdue University||Weldon School of Biomedical Engineering, Purdue University||Department of Neurobiology, University of Pittsburgh

10.1101/2022.03.16.484675

耳鼻咽喉科学神经病学、精神病学基础医学

Heinz Michael G.,Parida Satyabrata.Enhanced envelope coding following acoustic trauma is detrimental to neural coding of speech in noise[EB/OL].(2025-03-28)[2025-08-02].https://www.biorxiv.org/content/10.1101/2022.03.16.484675.点此复制

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