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Estimating the size of COVID-19 epidemic outbreak

Estimating the size of COVID-19 epidemic outbreak

来源:medRxiv_logomedRxiv
英文摘要

Abstract In this work, we analyze the epidemic data of cumulative infected cases collected from many countries as reported by WHO starting from January 21st 2020 and up till March 21st 2020. Our inspection is motivated by the renormalization group (RG) framework. Here we propose the RG-inspired logistic function of the form as an epidemic strength function with n being asymmetry in the modified logistic function. We perform the non-linear least-squares analysis with data from various countries. The uncertainty for model parameters is computed using the squared root of the corresponding diagonal components of the covariance matrix. We carefully divide countries under consideration into 2 categories based on the estimation of the inflection point: the maturing phase and the growth-dominated phase. We observe that long-term estimations of cumulative infected cases of countries in the maturing phase for both n = 1 and n ≠ 1 are close to each other. We find from the value of root mean squared error (RMSE) that the RG-inspired logistic model with n ≠ 1 is slightly preferable in this category. We also argue that n determines the characteristic of the epidemic at an early stage. However, in the second category, the estimated asymptotic number of cumulative infected cases contain rather large uncertainty. Therefore, in the growth-dominated phase, we focus on using n = 1 for countries in this phase. Some of them are in an early stage of an epidemic with an insufficient amount of data leading to a large uncertainty on parameter fits. In terms of the accuracy of the size estimation, the results do strongly depend on limitations on data collection and the epidemic phase for each country.

Channuie Phongpichit、Dam-O Punsiri、Samart Daris、Koomhin Phanit、Pongkitivanichkul Chakrit、Tangphati Takol、Payaka Apirak、Pimton Pimchanok

Research Group in Applied, Computational and Theoretical Science (ACTS), Walailak University||School of Science, Walailak University||College of Graduate Studies, Walailak UniversityResearch Group in Applied, Computational and Theoretical Science (ACTS), Walailak University||School of Science, Walailak UniversityDepartment of Physics, Faculty of Science, Khon Kaen UniversitySchool of Medicine, Walailak University||Research Group in Applied, Computational and Theoretical Science (ACTS), Walailak UniversityDepartment of Physics, Faculty of Science, Khon Kaen UniversityDepartment of Physics, Faculty of Science, Chulalongkorn UniversityResearch Group in Applied, Computational and Theoretical Science (ACTS), Walailak University||School of Science, Walailak University||College of Graduate Studies, Walailak UniversityResearch Group in Applied, Computational and Theoretical Science (ACTS), Walailak University||School of Science, Walailak University||Plasmas and Electromagnetic Wave Science (PEwave) Center of Excellence, Walailak University

10.1101/2020.03.28.20044339

医学研究方法基础医学数学

Channuie Phongpichit,Dam-O Punsiri,Samart Daris,Koomhin Phanit,Pongkitivanichkul Chakrit,Tangphati Takol,Payaka Apirak,Pimton Pimchanok.Estimating the size of COVID-19 epidemic outbreak[EB/OL].(2025-03-28)[2025-05-14].https://www.medrxiv.org/content/10.1101/2020.03.28.20044339.点此复制

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