Novel characterization of peptidergic release from prefrontal cortical somatostatin neurons
Novel characterization of peptidergic release from prefrontal cortical somatostatin neurons
ABSTRACT Somatostatin is a neuropeptide thought to play a role in a variety of neuropsychiatric disorders, and is important for healthy aging and behavioral resiliency. Conditions governing somatostatin peptidergic release are not well-defined. Using a combination of optogenetic, transgenic, and biochemical approaches, we demonstrate an assay for the induction and inhibition of somatostatin in acute brain slices.
Brockway Dakota F.、Crowley Nicole A.、Dao Nigel
Department of Biobehavioral Health, Pennsylvania State University||Neuroscience Curriculum, Pennsylvania State UniversityDepartment of Biobehavioral Health, Pennsylvania State University||Neuroscience Curriculum, Pennsylvania State UniversityDepartment of Biobehavioral Health, Pennsylvania State University
基础医学神经病学、精神病学生物科学研究方法、生物科学研究技术
Brockway Dakota F.,Crowley Nicole A.,Dao Nigel.Novel characterization of peptidergic release from prefrontal cortical somatostatin neurons[EB/OL].(2025-03-28)[2025-04-26].https://www.biorxiv.org/content/10.1101/599829.点此复制
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