In-depth Temporal Transcriptome Profiling of Monkeypox and Host Cells using Nanopore Sequencing
In-depth Temporal Transcriptome Profiling of Monkeypox and Host Cells using Nanopore Sequencing
The recent Monkeypox outbreak showed the importance of studying the basic biology of orthopoxviruses. However, the transcriptome of its causative agent has not been investigated before neither with short-, nor with long-read sequencing approaches. This Oxford Nanopore long-read RNA-Sequencing dataset fills this gap. Our direct cDNA and native RNA sequencing data enable the in-depth characterization of the transcriptomic architecture and dynamics of the gene expressions of monkeypox virus; and also the deeper understanding of the changes it causes in the host cells on a transcriptome level.
Holoubek Jiri、Kemenesi Gabor、Csabai Zsolt、Dormo Akos、Prazsak Istvan、Torma Gabor、Jakab Ferenc、Harangozo Akos、Fulop Adam、Gulyas Gabor、Mizik Mate、Tombacz Dora、Dani Virag Eva、Kiss Andras Attila、Denes Bela、Toth Gabor E、Ruzek Daniel、Zana Brigitta、Lanszki Zsofia、Foldes Fanni V、Boldogkoi Zsolt、Kakuk Balazs
生物科学研究方法、生物科学研究技术分子生物学微生物学
Holoubek Jiri,Kemenesi Gabor,Csabai Zsolt,Dormo Akos,Prazsak Istvan,Torma Gabor,Jakab Ferenc,Harangozo Akos,Fulop Adam,Gulyas Gabor,Mizik Mate,Tombacz Dora,Dani Virag Eva,Kiss Andras Attila,Denes Bela,Toth Gabor E,Ruzek Daniel,Zana Brigitta,Lanszki Zsofia,Foldes Fanni V,Boldogkoi Zsolt,Kakuk Balazs.In-depth Temporal Transcriptome Profiling of Monkeypox and Host Cells using Nanopore Sequencing[EB/OL].(2025-03-28)[2025-06-24].https://www.biorxiv.org/content/10.1101/2022.11.28.518226.点此复制
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