SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission
SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission
Abstract Oral swabs, sputum and blood samples from 18 patients with SARS-CoV-2 infection were examined using real-time reverse transcription polymerase chain reaction (RT-PCR) testing. Whereas oral swabs or sputum from the lower respiratory tract were tested RT-PCR positive in all patients, RNAemia was neither detected in 3 patients without symptoms nor in 14 patients with flu-like symptoms, fever or pneumonia. The only patient with RNAemia suffered from acute respiratory distress syndrome (ARDS) and was artificially ventilated in an intensive care unit. Risk for SARS-CoV-2 transmission through blood components in asymptomatic SARS-CoV-2 infected individuals therefore seems negligible but further studies are needed.
Ciesek Sandra、Rabenau Holger F.、Funk Markus B.、Corman Victor M.、Drosten Christian、Adams Ortwin、Keller-Stanislawski Brigitte、Oberle Doris、Timm J?rg
Institute for Medical Virology, University Hospital, Goethe University||DZIF, German Centre for Infection ResearchInstitute for Medical Virology, University Hospital, Goethe UniversityPaul-Ehrlich-Institut, Department Safety of Drugs and Medical DevicesCharit¨| University HospitalCharit¨| University Hospital||DZIF, German Centre for Infection ResearchInstitute for Virology, University Hospital D¨1sseldorf, Faculty of Medicine, University D¨1sseldorfPaul-Ehrlich-Institut, Department Safety of Drugs and Medical DevicesPaul-Ehrlich-Institut, Department Safety of Drugs and Medical DevicesInstitute for Virology, University Hospital D¨1sseldorf, Faculty of Medicine, University D¨1sseldorf
医学研究方法基础医学临床医学
Ciesek Sandra,Rabenau Holger F.,Funk Markus B.,Corman Victor M.,Drosten Christian,Adams Ortwin,Keller-Stanislawski Brigitte,Oberle Doris,Timm J?rg.SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission[EB/OL].(2025-03-28)[2025-05-31].https://www.medrxiv.org/content/10.1101/2020.03.29.20039529.点此复制
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