Convergent consequences of parthenogenesis on stick insect genomes
Convergent consequences of parthenogenesis on stick insect genomes
Abstract The shift from sexual reproduction to parthenogenesis has occurred repeatedly in animals, but how the loss of sex affects genome evolution remains poorly understood. We generated de novo reference genomes for five independently evolved parthenogenetic species in the stick insect genus Timema and their closest sexual relatives. Using these references in combination with population genomic data, we show that parthenogenesis results in an extreme reduction of heterozygosity, and often leads to genetically uniform populations. We also find evidence for less effective positive selection in parthenogenetic species, supporting the view that sex is ubiquitous in natural populations because it facilitates fast rates of adaptation. Contrary to studies of non-recombining genome portions in sexual species, genomes of parthenogenetic species do not accumulate transposable elements (TEs), likely because successful parthenogens derive from sexual ancestors with inactive TEs. Because we are able to conduct replicated comparisons across five species pairs, our study reveals, for the first time, how the absence of sex affects genome evolution in natural populations, providing empirical support for the negative consequences of parthenogenetic reproduction as predicted by theory.
Anselmetti Yoann、Dumas Zo¨|、Figuet Emeric、Hayward Keith、Rossier Victor、Simion Paul、Galtier Nicolas、Robinson-Rechavi Marc、Van Patrick Tran、Fran?ois Cl¨|mentine M.、Parker Darren J.、Jaron Kamil S.、Schwander Tanja、Bast Jens
ISEM - Institut des Sciences de l?ˉEvolution||CoBIUS lab, Department of Computer Science, University of SherbrookeDepartment of Ecology and Evolution, University of LausanneISEM - Institut des Sciences de l?ˉEvolutionDepartment of Ecology and Evolution, University of Lausanne||Swiss Institute of BioinformaticsDepartment of Ecology and Evolution, University of Lausanne||Swiss Institute of BioinformaticsISEM - Institut des Sciences de l?ˉEvolution||Universit¨| de Namur, LEGE, URBE, NamurISEM - Institut des Sciences de l?ˉEvolutionDepartment of Ecology and Evolution, University of Lausanne||Swiss Institute of BioinformaticsDepartment of Ecology and Evolution, University of Lausanne||Swiss Institute of BioinformaticsISEM - Institut des Sciences de l?ˉEvolution||Universit¨| Claude Bernard Lyon 1, CNRS, ENTPE, UMR 5023 LEHNADepartment of Ecology and Evolution, University of Lausanne||Swiss Institute of BioinformaticsDepartment of Ecology and Evolution, University of Lausanne||Swiss Institute of Bioinformatics||Institute of Evolutionary Biology, School of Biological Sciences, University of EdinburghDepartment of Ecology and Evolution, University of LausanneDepartment of Ecology and Evolution, University of Lausanne||Institute for Zoology, University of Cologne
遗传学昆虫学分子生物学
Anselmetti Yoann,Dumas Zo¨|,Figuet Emeric,Hayward Keith,Rossier Victor,Simion Paul,Galtier Nicolas,Robinson-Rechavi Marc,Van Patrick Tran,Fran?ois Cl¨|mentine M.,Parker Darren J.,Jaron Kamil S.,Schwander Tanja,Bast Jens.Convergent consequences of parthenogenesis on stick insect genomes[EB/OL].(2025-03-28)[2025-05-22].https://www.biorxiv.org/content/10.1101/2020.11.20.391540.点此复制
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