The Stone Age Plague: 1000 years of Persistence in Eurasia
The Stone Age Plague: 1000 years of Persistence in Eurasia
Abstract Molecular signatures of Yersinia pestis were recently identified in prehistoric Eurasian individuals, thus suggesting Y. pestis caused some form of disease in humans prior to the first historically documented pandemic. Here, we present six new Y. pestis genomes spanning from the European Late Neolithic to the Bronze Age (LNBA) dating from 4,800 to 3,700 BP. We show that all currently investigated LNBA strains form a single genetic clade in the Y. pestis phylogeny that appears to be extinct. Interpreting our data within the context of recent ancient human genomic evidence, which suggests an increase in human mobility during the LNBA, we propose a possible scenario for the spread of Y. pestis during the LNBA: Y. pestis may have entered Europe from Central Eurasia during an expansion of steppe people, persisted within Europe until the mid Bronze Age, and moved back towards Central Eurasia in parallel with subsequent human population movements.
T?rv Mari、Hansen Svend、Bos Kirsten I.、Massy Ken、Reinhold Sabine、Haak Wolfgang、Daubaras Mantas、Feldman Michal、Jankovi? Ivor、Key Felix M.、Szecsenyi-Nagy Anna、Allm?e Raili、Stockhammer Philipp W.、Krause Johannes、?laus Mario、Spyrou Maria A.、Herbig Alexander、Mittnik Alissa、Novak Mario、Valtue?a Aida Andrades、Belinskij Andrej、Pfrengle Saskia、Jankauskas Rimantas
Independent researcherEurasia Department, German Archaeological InstituteMax Planck Institute for the Science of Human History||Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of T¨1bingenInstitute for Pre- and Protohistoric Archaeology and Archaeology of the Roman Provinces, Ludwig-Maximilians-University Munich||Heidelberg Academy of SciencesEurasia Department, German Archaeological InstituteMax Planck Institute for the Science of Human History||School of Biological Sciences, The University of AdelaideDepartment of Archaeology, Lithuanian Institute of HistoryMax Planck Institute for the Science of Human History||Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of T¨1bingenInstitute for anthropological research||Department of Anthropology, University of WyomingMax Planck Institute for the Science of Human HistoryInstitute of Archaeology, Research Centre for the Humanities, Hungarian Academy of SciencesArchaeological Research Collection, Tallinn UniversityMax Planck Institute for the Science of Human History||Institute for Pre- and Protohistoric Archaeology and Archaeology of the Roman Provinces, Ludwig-Maximilians-University MunichMax Planck Institute for the Science of Human History||Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of T¨1bingenAnthropological Center, Croatian Academy of Sciences and ArtsMax Planck Institute for the Science of Human History||Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of T¨1bingenMax Planck Institute for the Science of Human History||Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of T¨1bingenMax Planck Institute for the Science of Human History||Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of T¨1bingenInstitute for anthropological researchMax Planck Institute for the Science of Human History?°Nasledie?± Cultural Heritage UnitInstitute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of T¨1bingenDepartment of Anatomy, Histology and Anthropology, Vilnius University
微生物学史学理论亚洲史欧洲史
T?rv Mari,Hansen Svend,Bos Kirsten I.,Massy Ken,Reinhold Sabine,Haak Wolfgang,Daubaras Mantas,Feldman Michal,Jankovi? Ivor,Key Felix M.,Szecsenyi-Nagy Anna,Allm?e Raili,Stockhammer Philipp W.,Krause Johannes,?laus Mario,Spyrou Maria A.,Herbig Alexander,Mittnik Alissa,Novak Mario,Valtue?a Aida Andrades,Belinskij Andrej,Pfrengle Saskia,Jankauskas Rimantas.The Stone Age Plague: 1000 years of Persistence in Eurasia[EB/OL].(2025-03-28)[2025-05-29].https://www.biorxiv.org/content/10.1101/094243.点此复制
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