Crowdsourced analysis of ash and ash dieback through the Open Ash Dieback project: A year 1 report on datasets and analyses contributed by a self-organising community
Crowdsourced analysis of ash and ash dieback through the Open Ash Dieback project: A year 1 report on datasets and analyses contributed by a self-organising community
Abstract Ash dieback is a fungal disease of ash trees caused by Hymenoscyphus pseudoalbidus that has swept across Europe in the last two decades and is a significant threat to the ash population. This emergent pathogen has been relatively poorly studied and little is known about its genetic make-up. In response to the arrival of this dangerous pathogen in the UK we took the unusual step of providing an open access database and initial sequence datasets to the scientific community for analysis prior to performing an analysis of our own. Our goal was to crowdsource genomic and other analyses and create a community analysing this pathogen. In this report on the evolution of the community and data and analysis obtained in the first year of this activity, we describe the nature and the volume of the contributions and reveal some preliminary insights into the genome and biology of H. pseudoalbidus that emerged. In particular our nascent community generated a first-pass genome assembly containing abundant collapsed AT-rich repeats indicating a typically complex genome structure. Our open science and crowdsourcing effort has brought a wealth of new knowledge about this emergent pathogen within a short time-frame. Our community endeavour highlights the positive impact that open, collaborative approaches can have on fast, responsive modern science.
Sambles Christine、Bunting Daniel、Collin Steve、Hosoya Tsuyoshi、Edwards Anne、Crossman Lisa、Etherington Graham、Win Joe、Cano Liliana、Studholme David J.、Downie J. Allan、Kamoun Sophien、MacLean Dan、Dong Suomeng、Clark Matthew D.、Corpas Manuel、Ayling Sarah、Glover Rachel、Bashton Matthew、Rallapalli Ghanasyam、Saunders Diane、Caccamo Mario、Yoshida Kentaro、Clavijo Bernardo、Swarbreck David
The University of Exeter, Department of BiosciencesThe Sainsbury Laboratory, Norwich Research ParkNorfolk Wildlife TrustNational Museum of Nature and ScienceThe John Innes Centre, Norwich Research ParkSequenceAnalysis.co.uk, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe University of Exeter, Department of BiosciencesThe John Innes Centre, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe Genome Analysis Centre, Norwich Research ParkThe Genome Analysis Centre, Norwich Research ParkThe Genome Analysis Centre, Norwich Research ParkThe Food and Environment Research AgencyNewcastle UniversityThe Sainsbury Laboratory, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe Genome Analysis Centre, Norwich Research ParkThe Sainsbury Laboratory, Norwich Research ParkThe Genome Analysis Centre, Norwich Research ParkThe Genome Analysis Centre, Norwich Research Park
生物科学现状、生物科学发展环境生物学植物学
Sambles Christine,Bunting Daniel,Collin Steve,Hosoya Tsuyoshi,Edwards Anne,Crossman Lisa,Etherington Graham,Win Joe,Cano Liliana,Studholme David J.,Downie J. Allan,Kamoun Sophien,MacLean Dan,Dong Suomeng,Clark Matthew D.,Corpas Manuel,Ayling Sarah,Glover Rachel,Bashton Matthew,Rallapalli Ghanasyam,Saunders Diane,Caccamo Mario,Yoshida Kentaro,Clavijo Bernardo,Swarbreck David.Crowdsourced analysis of ash and ash dieback through the Open Ash Dieback project: A year 1 report on datasets and analyses contributed by a self-organising community[EB/OL].(2025-03-28)[2025-05-23].https://www.biorxiv.org/content/10.1101/004564.点此复制
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