基于GC/MS方法对毒品原植株上罂粟碱分布的研究

Objective Analyzed by GC-MS,A model for the distribution of papaverine in the original plant was established. Methods Different parts of the original opium poppy plant 100 mg, The supernatant was obtained by acidizing 5 ml 0.5% glacial acetic acid solution.Adjust to ph = 8.7 alkaline,Add 2 ml of the extract (Chloroform: isopropyl alcohol = 3:1),After 30 min of ultrasound, the liquid was removed by centrifugation,and then analyzed by GC-MS under EI. Results The components of papaverine in different parts of the original drug plant were analyzedIt was found that the order of papaverine content from low to high was root < stem < leaf < flower < frui;Papaverine was not found in plant seeds;Papaverine content in papaverine seedlings was extremely low,Only after concentration and volume determination can it be detected. Conclusions The content and distribution of papaverine in the original plants were analyzed systematically, It filled the blank of the study on the distribution of papaverine in the original drug plants in China, Therefore, It provides the reference of GC-MS method and original value drug strain cases for the laboratories that encounter similar cases in the future.