A data first approach to modelling Covid-19
A data first approach to modelling Covid-19
Abstract The primary data for Covid-19 pandemic is in the form of time series for the number of confirmed, recovered and dead cases. This data is updated every day and is available for most countries from multiple sources such as [Gar20b, iD20]. In this work we present a two step procedure for model fitting to Covid-19 data. In the first step, time dependent transmission coefficients are constructed directly from the data and, in the second step, measures of those (minimum, maximum, mean, median etc.,) are used to set priors for fitting models to data. We call this approach a “data driven approach” or “data first approach”. This scheme is complementary to Bayesian approach and can be used with or without that for parameter estimation. We use the procedure to fit a set of SIR and SIRD models, with time dependent contact rate, to Covid-19 data for a set of 45 most affected countries. We find that SIR and SIRD models with constant transmission coefficients cannot fit Covid-19 data for most countries (mainly because social distancing, lockdown etc., make those time dependent). We find that any time dependent contact rate, which falls gradually with time, can help to fit SIR and SIRD models for most of the countries. We also present constraints on transmission coefficients and basic reproduction number ?0 as well as effective reproduction number ?(t). The main contributions of our work are as follows. (1) presenting a two step procedure for model fitting to Covid-19 data (2) constraining transmission coefficients as well as ?0 and ?(t), for a set of most affected countries and (3) releasing a python package PyCov19 [Pra20] that can used to fit a set of compartmental models with time varying coefficients to Covid-19 data.
Prasad Jayanti
Khagol-20
医学研究方法基础医学计算技术、计算机技术
Prasad Jayanti.A data first approach to modelling Covid-19[EB/OL].(2025-03-28)[2025-05-01].https://www.medrxiv.org/content/10.1101/2020.05.22.20110171.点此复制
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