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Impact of a pilot community pharmacy system redesign on reducing over-the-counter medication misuse in older adults

Impact of a pilot community pharmacy system redesign on reducing over-the-counter medication misuse in older adults

来源:medRxiv_logomedRxiv
英文摘要

Abstract ObjectivesThis pilot study examines effectiveness of an innovative pharmacy design change on over-the-counter (OTC) medication misuse in older adults (ages ≥65). Few interventions have attempted to decrease older adult OTC misuse, and none have addressed system barriers. A structural redesign of the pharmacy (the Senior Section?) was conceptualized to increase awareness of higher-risk OTC medications. The Senior Section contains a curated selection of OTC medications (for pain, cough/cold, allergy, sleep) and is close to the prescription department to facilitate pharmacy staff/patient engagement to reduce misuse. MethodsA pre-/post-implementation design was used to recruit 87 older adults from three pharmacies. Using a hypothetical scenario, participants selected an OTC medication, which was compared to their medication list and health conditions, and their reported use was compared against the product labeling. Four misuse outcomes were determined: (1) Drug/Drug, (2) Drug/Disease, (3) Drug/Age, and (4) Drug/Label with five sub-types. Patient characteristics were collected and compiled into a propensity-score matching logistic regression model to estimate their effects on the Senior Section’s association with misuse outcomes at pre-/post-implementation. ResultsPatient characteristic were uniform between pre-/post-implementation and, once entered into a propensity-score matching model, Drug/Disease Misuse significantly lessened over time (z=-2.09, p=0.037). The Senior Section reduced Drug/Drug Misuse, but not significantly. Drug/Label Misuse varied according to the sub-type, with reduced Daily-Dosage (z=-2.42, p=0.016) and Single-Dosage misuse (z=-5.82, p=0.001); however, Timing/Frequency misuse increased (z=2.16, p=0.031). ConclusionsThese nascent outcomes support a well-conceived pharmacy-based OTC aisles redesign as valuable for reducing older adult OTC medication misuse. The Senior Section, when broadly implemented, would create new permanent structures and processes to assist older adults in accessing risk information for confidently selecting safer OTC medications.

Jacobson Nora、Phelan Cynthia H.、Gilson Aaron M.、Brown Roger L.、Albert Steven M.、Pigarelli Denise L. Walbrandt、Breslow Robert M.、Xiong Ka Z、Stone Jamie A.、Welch Lauren、Chui Michelle A.、Holden Richard J.、Morris Ashley O.

Institute for Clinical and Translational Research, Community Academic Partnerships Program, University of Wisconsin-MadisonCenter for Nursing Research and Practice, Aurora Sinai HospitalSonderegger Research Center, University of Wisconsin-Madison School of PharmacyDirector of Research Design and Statistics Unit, Schools of Nursing, Medicine and Public Health, University of Wisconsin-MadisonDepartment of Behavioral and Community Health Sciences, Graduate School of Public Health, University of PittsburghDivision of Pharmacy Practice, University of Wisconsin-Madison School of PharmacyDivision of Pharmacy Practice, University of Wisconsin-Madison School of PharmacySocial and Administrative Sciences Division, University of Wisconsin-Madison School of PharmacySocial and Administrative Sciences Division, University of Wisconsin-Madison School of PharmacyWilliam S Middleton VA Geriatrics Research Education & Clinical Center (GRECC)Social and Administrative Sciences Division, University of Wisconsin-Madison School of PharmacyDepartment of Medicine, Indiana University School of Medicine, Indiana University Center for Aging Research, Regenstrief InstituteSocial and Administrative Sciences Division, University of Wisconsin-Madison School of Pharmacy

10.1101/2019.12.19.19014886

医药卫生理论药学预防医学

Jacobson Nora,Phelan Cynthia H.,Gilson Aaron M.,Brown Roger L.,Albert Steven M.,Pigarelli Denise L. Walbrandt,Breslow Robert M.,Xiong Ka Z,Stone Jamie A.,Welch Lauren,Chui Michelle A.,Holden Richard J.,Morris Ashley O..Impact of a pilot community pharmacy system redesign on reducing over-the-counter medication misuse in older adults[EB/OL].(2025-03-28)[2025-08-02].https://www.medrxiv.org/content/10.1101/2019.12.19.19014886.点此复制

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