血清铁在中老年社区获得性肺炎疾病识别的相关性评估
he correlation assessment of serum iron in the identification of community-acquired pneumonia in middle-aged and elderly individuals
目的 探究血清铁在中老年社区获得性肺炎（community-acquired pneumonia，CAP）疾病识别的相关性研究。方法 纳入2019年10月~2024年07月我院住院治疗的中老年CAP患者137例，收集临床资料、检验检查数据，研究与血清铁之间的关系。采用二元Logistic回归分析对血清铁造成影响的危险因素。绘制受试者操作特征（receiver operating characteristic，ROC）曲线评价独立影响因素及联合应用预测效能。结果 白细胞（white blood cells，WBC）、C-反应蛋白（c-reactive protein，CRP）、降钙素原（procalcitonin，PCT）、D-二聚体（D-D）、感染部位及感染范围是导致血清铁异常的危险因素。上述六项指标单独预测中老年CAP患者发生血清铁异常的曲线下面积（area under the curve，AUC）分别为0.755、0.730、0.676、0.725、0.594、0.628，联合预测的AUC为0.883。结论 血清铁水平变化与中老年CAP疾病识别存在一定关联。
Objective To investigate the correlation between serum iron and the disease identification of community-acquired pneumonia (CAP) in middle-aged and elderly patients. Methods Retrieve middle-aged and elderly CAP patients (n=137) who were hospitalized in our hospital from October 2019 to July 2024. Collect clinical data, test and examine indicators, and study the relationship between serum iron level. Use binary logistic regression analysis to identify the risk factors affecting serum iron levels. Draw receiver operating characteristic curves to evaluate the predictive performance of independent influencing factors and combined applications. Results White blood cells (WBC), C-reactive protein (CRP), procalcitonin (PCT), d-dimer (D-D), infection site and range are risk factors for serum iron abnormalities. The AUC of predicting serum iron abnormalities in middle-aged and elderly CAP patients using the above six indicators separately are 0.755, 0.730, 0.676, 0.725, 0.594, and 0.628. The joint predicted AUC is 0.883. Conclusion There is a certain correlation between changes in serum iron levels and the recognition of CAP disease in middle-aged and elderly people.
赵伟丹、黄旭日、肖岑昕
临床医学内科学
社区获得性肺炎血清铁中老年
ommunity acquired pneumonia Serum iron Middle aged and elderly
赵伟丹,黄旭日,肖岑昕.血清铁在中老年社区获得性肺炎疾病识别的相关性评估[EB/OL].(2024-10-17)[2025-07-01].https://www.biomedrxiv.org.cn/article/doi/bmr.202501.00002.点此复制
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