Emergence and spread of SARS-CoV-2 lineages B.1.1.7 and P.1 in Italy
Emergence and spread of SARS-CoV-2 lineages B.1.1.7 and P.1 in Italy
Abstract Italy’s second wave of SARS-CoV-2 has hit hard, with more than 3 million cases and over 100,000 deaths, representing an almost ten-fold increase on the numbers reported by August 2020. Herein, we present the analysis of 6,515 SARS-CoV-2 sequences sampled in Italy between 29th January 2020 and 1st March 2021 and show how different lineages emerged multiple times independently despite lockdown restrictions. Virus lineage B.1.177 became the dominant variant in November 2020, when cases peaked at 40,000 a day, but since January 2021 this is being replaced by the B.1.1.7 ‘variant of concern’. In addition, we report a sudden increase in another documented variant of concern – lineage P.1 – from December 2020 onwards, most likely caused by a single introduction into Italy. We again highlight how international importations drive the emergence of new lineages and that genome sequencing should remain a top priority for ongoing surveillance in Italy.
Puglia Ilaria、Di Giallonardo Francesca、Camm¨¤ Cesare、Curini Valentina、Cobbin Joanna C.A.、Holmes Edward C.、Calistri Paolo、Lorusso Alessio、Mangone Iolanda
Istituto Zooprofilattico Sperimentale dell?ˉAbruzzo e del Molise G. CaporaleThe Kirby Institute, UNSW SydneyIstituto Zooprofilattico Sperimentale dell?ˉAbruzzo e del Molise G. CaporaleIstituto Zooprofilattico Sperimentale dell?ˉAbruzzo e del Molise G. CaporaleMarie Bashir Institute for Infectious Diseases and Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of SydneyMarie Bashir Institute for Infectious Diseases and Biosecurity, School of Life & Environmental Sciences and School of Medical Sciences, The University of SydneyIstituto Zooprofilattico Sperimentale dell?ˉAbruzzo e del Molise G. CaporaleIstituto Zooprofilattico Sperimentale dell?ˉAbruzzo e del Molise G. CaporaleIstituto Zooprofilattico Sperimentale dell?ˉAbruzzo e del Molise G. Caporale
医学现状、医学发展医学研究方法微生物学
Puglia Ilaria,Di Giallonardo Francesca,Camm¨¤ Cesare,Curini Valentina,Cobbin Joanna C.A.,Holmes Edward C.,Calistri Paolo,Lorusso Alessio,Mangone Iolanda.Emergence and spread of SARS-CoV-2 lineages B.1.1.7 and P.1 in Italy[EB/OL].(2025-03-28)[2025-08-02].https://www.medrxiv.org/content/10.1101/2021.03.24.21254277.点此复制
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