Quantitative susceptibility mapping improves the detection of calcified carotid vessels by multi-contrast MRI using computed tomography angiography as the reference standard
Quantitative susceptibility mapping improves the detection of calcified carotid vessels by multi-contrast MRI using computed tomography angiography as the reference standard
Abstract The objective of this study was to evaluate initial feasibility and improvement in the detection of calcified carotid arteries by including quantitative susceptibility mapping (QSM) in the carotid vessel wall multi-contrast MRI (mcMRI) protocol using CTA as the reference standard. In a pilot cohort of ten patients with significant carotid artery stenosis, calcified vessel detection by mcMRI achieved 64.7% sensitivity and 100% specificity. Adding QSM to mcMRI improved sensitivity to 100% while not affecting specificity.
Du Jingwen、Qi Yang、Gupta Ajay、Wen Yan、Kamel Hooman、Spincemaille Pascal、Wang Yi、Nguyen Thanh D.
Xuanwu Hospital, Capital Medical UniversityXuanwu Hospital, Capital Medical UniversityRadiology, Weill Cornell Medicine||Feil Family Brain and Mind Research Institute, Weill Cornell MedicineRadiology, Weill Cornell Medicine||Meinig School of Biomedical Engineering, Cornell UniversityNeurology, Weill Cornell Medicine||Feil Family Brain and Mind Research Institute, Weill Cornell MedicineRadiology, Weill Cornell MedicineRadiology, Weill Cornell Medicine||Meinig School of Biomedical Engineering, Cornell UniversityRadiology, Weill Cornell Medicine
医学研究方法临床医学神经病学、精神病学
Du Jingwen,Qi Yang,Gupta Ajay,Wen Yan,Kamel Hooman,Spincemaille Pascal,Wang Yi,Nguyen Thanh D..Quantitative susceptibility mapping improves the detection of calcified carotid vessels by multi-contrast MRI using computed tomography angiography as the reference standard[EB/OL].(2025-03-28)[2025-06-08].https://www.medrxiv.org/content/10.1101/2021.07.07.21260049.点此复制
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