膝骨关节炎患者衰弱研究的范围综述

BackgroundKnee osteoarthritisKOA is the fourth most disabling disease globallywith an increasing incidence and disability rate. Frailty is associated with KOA and significantly reduces the quality of life of KOA patients. ObjectiveTo conduct a scoping review of the current status of frailty in KOA patientsassessment toolsinfluencing factorsand intervention measuresin order to provide theoretical support for early prediction of frailty progression and personalized intervention measures. MethodsA systematic review was conducted using a combination of subject headings and free terms to search for relevant studies on the prevalenceassessment toolsinfluencing factorsand intervention methods for frailty in patients with KOA in Web of SciencePubMedEmbaseCochrane LibraryCNKIWanfang Data Knowledge Service PlatformVIPand China Biomedical Database. The search period was from the establishment of the databases to December 122024. Two researchers independently summarizedcategorizedand analyzed the literature data. ResultsA total of 13 articles were finally included. The study results showed that the incidence of frailty in KOA patients was 8.2% to 67.8%and the incidence and severity of frailty in patients were different in different studies. There are many types of assessment toolsbut there is a lack of specific assessment tools in general. The commonly used tools in the study were the SOF indexthe FRAIL scaleand the Fried phenotype. The influencing factors mainly include demographic and social factorsdisease-related factorsand psychological and behavioral factors. The intervention measures include exercise trainingcombined traditional Chinese medicine and exercise therapyand injection therapy. ConclusionThe incidence of frailty in KOA patients varies to some extentthere is a lack of specific assessment tools at presentand a more suitable frailty prediction assessment tool for KOA patients in China can be compiled in the future to provide a time node for precise intervention of frailty. Meanwhileefforts should be made to focus on the risk factors that affect the frailty of KOA patients to delay the progression of frailty and improve their quality of life.