孕晚期女性膳食炎症指数和泌乳启动延迟的相关性研究

BackgroundDelayed onset of lactogenesisDOL is an important cause of reduced exclusive breastfeeding rates. The dietary inflammatory indexDII has been shown to be associated with a variety of adverse health outcomesbut the relationship with DOL is not well understood. ObjectiveUnderstanding DII levels in the third trimester and exploring their impact on DOL. MethodsA convenience sampling method was used to select women in the third trimester who underwent routine obstetric examinations at the First Affiliated Hospital of Anhui Medical University from December 2023 to June 2024 as the study subjects and were followed up until 72 hours postpartumand the maternal self-perceived breast distension method was used to determine whether they were in the DOL population. General demographic characteristics and information related to pregnancy and childbirth were collected by using a general information questionnairea food frequency questionnaireFFQ was used to collect information on dietary intake and calculates the DIIand the delivery and postpartum data questionnaire collected relevant information about labor and postpartum. Exploring the relationship between DII and DOL using binary logistic regression analysis and stratified the factors of Agepreconception BMIand presence of gestational diabetes mellitus. ResultsA total of 228 questionnaires were distributed and 217 questionnaires were validly returnedwith an effective return rate of 95.2%. Among them6831.3%had DOL. The DOL and the non-DOL mothers were statistically different in terms of the number of pregnanciesthe quality of sleepgestational weight gainand the presence of mother-infant separation after deliveryP<0.05. The pregnant women in the high DII group had a higher incidence of DOL than those in the middle and low DII groups according to the three quartiles of DII scores from smallest to largestP<0.05. The results of binary Logistic regression analysis showed that the risk of DOL was 2.817 times higher in the high DII group than in the low DII group95%CI=1.244~6.381P=0.013. In the third trimester group of women aged<35 years with preconception BMI<24.0 kg/m2 the risk of DOL in women with high DII levels was 3.144 times95%CI=1.346-7.344P<0.05 and 2.666 times 95%CI=1.072-6.630P<0.05 higher than in women with low DII levelsrespectively. ConclusionThere was a correlation between DII and DOLwith higher DII increasing the risk of DOLespecially in the group of women in late pregnancy who are <35 years of age and with preconception BMI <24.0 kg/m2 . Maternal and child health care providers should provide individualized dietary guidance to pregnant women to increase the intake of anti-inflammatory diets to reduce the incidence of DOL and increase the rate of exclusive breastfeeding.