免疫检查点抑制剂相关性甲状腺功能减退的中西医诊疗进展
免疫检查点抑制剂(immune checkpoint inhibitors,ICIs)相关性甲状腺功能减退是肿瘤免疫治疗中较为常见的一种免疫相关性不良反应,严重的ICIs相关性甲减不仅会使患者的治疗中断,还会影响患者的生活质量以及预后。西医治疗主要以补充甲状腺激素为主,而中医则从整体出发,进行个性化的辨证施治。现将近年来ICIs相关性甲状腺功能减退在中西医领域的研究进展展开概述。
Immune checkpoint inhibitors (ICIs)-associated hypothyroidism is a common immune-related adverse reaction in tumor immunotherapy, and severe ICIs-associated hypothyroidism will not only interrupt the treatment of patients, but also affect the quality of life and prognosis of patients. Western medicine mainly focuses on thyroid hormone supplementation, while TCM takes a holistic approach to individualized syndrome differentiation. This article summarizes the research progress of ICIs-related hypothyroidism in the field of traditional Chinese and Western medicine in recent years.
王欢、马莹、田婧楠、卢义、王亚楠
吉林省肿瘤医院湖光院区吉林省肿瘤医院湖光院区长春中医药大学吉林省肿瘤医院湖光院区长春中医药大学
医学现状、医学发展中医学临床医学
免疫检查点抑制剂甲状腺功能减退中西医研究进展
Immune checkpoint inhibitorsHypothyroidismraditional Chinese and Western MedicineResearch progress
王欢,马莹,田婧楠,卢义,王亚楠.免疫检查点抑制剂相关性甲状腺功能减退的中西医诊疗进展[EB/OL].(2025-04-14)[2025-05-28].https://www.biomedrxiv.org.cn/article/doi/bmr.202505.00004.点此复制
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