湘潭地区白色念珠菌和光滑念珠菌的耐药特征

andida is a kind of important opportunistic pathogenic fungi. Among them, infections caused by Candida albicans, Candida glabra, etc. are widespread in hospitals and communities, seriously threatening global human health. Fluconazole, as a first-line drug for the treatment of candida infections, has led to increasingly prominent drug resistance problems due to long-term use. Due to differences in the health status of the regional population, antibiotic medication habits, medical and health conditions, as well as the climate and environment of the region, the clinical distribution of candida infections shows significant regional differences. This study aims to conduct an epidemiological investigation of Candida albicans and Candida glabra infections in Xiangtan area and further explore the intrinsic connection between drug efflux pumps and fluconazole resistance, providing a scientific basis for formulating precise anti-Candida infection prevention and control strategies and optimizing clinical medication regimens in this area.