类器官在眼科研究中的应用

Ophthalmic organoid technology, as an important tool for tissue engineering and disease modeling, has made remarkable progress in recent years in various ocular tissues such as the cornea, lens, and retina. Through a variety of three-dimensional induction methods, the resulting organoids not only possess tissue-specific structures and functions but also recapitulate eye development processes and reflect corresponding pathological changes. Current research focuses on improving induction efficiency, enhancing structural complexity, and increasing biological similarity to native tissues. Ophthalmic organoids provide a physiologically relevant experimental platform for investigating ocular tissue development mechanisms, constructing disease models, and conducting drug screening and efficacy evaluations, thereby significantly advancing both basic and translational research in ophthalmology.