Adverse Event Extraction from Discharge Summaries: A New Dataset, Annotation Scheme, and Initial Findings
Adverse Event Extraction from Discharge Summaries: A New Dataset, Annotation Scheme, and Initial Findings
In this work, we present a manually annotated corpus for Adverse Event (AE) extraction from discharge summaries of elderly patients, a population often underrepresented in clinical NLP resources. The dataset includes 14 clinically significant AEs-such as falls, delirium, and intracranial haemorrhage, along with contextual attributes like negation, diagnosis type, and in-hospital occurrence. Uniquely, the annotation schema supports both discontinuous and overlapping entities, addressing challenges rarely tackled in prior work. We evaluate multiple models using FlairNLP across three annotation granularities: fine-grained, coarse-grained, and coarse-grained with negation. While transformer-based models (e.g., BERT-cased) achieve strong performance on document-level coarse-grained extraction (F1 = 0.943), performance drops notably for fine-grained entity-level tasks (e.g., F1 = 0.675), particularly for rare events and complex attributes. These results demonstrate that despite high-level scores, significant challenges remain in detecting underrepresented AEs and capturing nuanced clinical language. Developed within a Trusted Research Environment (TRE), the dataset is available upon request via DataLoch and serves as a robust benchmark for evaluating AE extraction methods and supporting future cross-dataset generalisation.
Imane Guellil、Salomé Andres、Atul Anand、Bruce Guthrie、Huayu Zhang、Abul Hasan、Honghan Wu、Beatrice Alex
医学研究方法临床医学
Imane Guellil,Salomé Andres,Atul Anand,Bruce Guthrie,Huayu Zhang,Abul Hasan,Honghan Wu,Beatrice Alex.Adverse Event Extraction from Discharge Summaries: A New Dataset, Annotation Scheme, and Initial Findings[EB/OL].(2025-06-17)[2025-07-02].https://arxiv.org/abs/2506.14900.点此复制
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