乌灵胶囊联合酒石酸唑吡坦片治疗失眠的疗效观察

Abstract Objective: To explore and compare the effect difference of Wuling Capsules and zolpidem tartrate tablets in the treatment of insomnia patients, and to compare and analyze the clinical benefits of the combined medication scheme and single sedative-hypnotic drugs intervention. Methods: the information system of our hospital was retrieved to collect the clinical data of insomnia patients with heart kidney disharmony in our hospital outpatient department from December 2024 to March 2025 as research materials. According to the treatment method, they were divided into observation group and control group, with 30 cases in each group (the observation group was treated with Wuling capsule combined with zolpidem tartrate, and the control group was treated with zolpidem tartrate alone). The observation indexes of sleep quality evaluation index (Pittsburgh sleep quality index PSQI), TCM syndrome score, insomnia severity index (ISI) and mental health evaluation dimension (including self rating Anxiety Scale SAS and self rating Depression Scale SDS) of the two groups before and after treatment were compared. Results: after 2 weeks of clinical intervention, compared with the control group, the observation group showed a more significant trend of symptom improvement in PSQI, TCM symptom score, ISI, SAS, SDS and other dimensions（P＜0.05）. Conclusion: compared with zolpidem tartrate tablets alone, Wuling capsule combined with zolpidem tartrate tablets has better curative effect in the treatment of insomnia patients with heart kidney disharmony, lower PSQI score and more obvious emotional improvement.