Review: Adaptive Radiation Therapy for Head and Neck Cancer

The future of ART in head and neck cancer is just beginning. Novel technologies have pushed the boundary of what is possible in terms of techniques to identify biomarkers for adaptation as well as innovative devices specialized to respond to these adaptations, sometimes in real-time. Important interdisciplinary steps must be taken moving forward to ensure the safe deployment of these new techniques, such as rigorous quality assurance evaluations from medical physicists, clinical trials from physicians, and comprehensive testing from vendors prior to release. In summary, we aimed not to provide a single correct answer for the optimal implementation of ART in the era of imaging biomarkers, but to encourage the field to collaborate and bring each idea discussed here together to overcome current barriers and deliver the best treatment possible to the patient.