椎动脉型颈椎病病理机制研究现状
Current Research St atus on the Pathological Mechanisms of Vertebral Artery Type Cervical Spondylosis
乌日古木拉 1于天源 1张英琦1
作者信息
- 1. 北京中医药大学针灸推拿学院，北京 100029
- 折叠
摘要
椎动脉型颈椎病是颈椎退变引发椎-基底动脉供血不足所致。其发病机制复杂，涉及骨性压迫、交感神经刺激、体液因子紊乱及血液流变学异常等多因素相互作用，引发眩晕、头疼、视力模糊等临床症状。本文系统综述了CSA的病理机制研究现状，重点阐述了机械压迫学说、颈交感神经学说、体液学说及血液流变学异常的分子基础，为CSA的机制研究提供参考。
Abstract
Vertebrobasilar type cervical spondylosis is caused by insufficient blood supply to the vertebrobasilar system resulting from degenerative changes in the cervical spine. Its pathogenesis is complex, involving the interaction of multiple factors such as bony compression, sympathetic nerve stimulation, disturbances in humoral factors, and abnormalities in blood rheology, leading to clinical symptoms such as dizziness, headaches and blurred vision. This article provides a systematic review of the current state of research into the pathophysiological mechanisms of cervical spondylocerebrovascular disease (CSA), focusing on the molecular basis of the mechanical compression hypothesis, the cervical sympathetic nerve hypothesis, the humoral hypothesis, and abnormalities in blood rheology, thereby offering a reference for further research into the mechanisms of CSA.关键词
椎动脉型颈椎病/病理机制/骨性压迫/交感神经/椎基底动脉供血不足Key words
Vertebral artery type cervical spondylosis/Pathological mechanisms/Osteogenic compression/Sympathetic nerves/Vertebrobasilar insufficiency引用本文复制引用
乌日古木拉,于天源,张英琦.椎动脉型颈椎病病理机制研究现状[EB/OL].(2026-03-24)[2026-03-26].http://www.paper.edu.cn/releasepaper/content/202603-241.学科分类
基础医学
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