非编码RNA及RNA结合蛋白在棉花纤维发育中的功能研究进展
Research progress on the functions of non-coding RNAs and RNA-binding proteins in cotton fiber development
张硕 1谷淇深 1孙正文 1张冬梅 1张艳 1马峙英 1王省芬1
作者信息
- 1. 河北农业大学农学院，保定，071000
- 折叠
摘要
棉花纤维发育是研究植物单细胞生长的理想模型，其高度时空精确性依赖转录后调控。本文系统综述了非编码RNA（miRNA、lncRNA、siRNA）与RNA结合蛋白在棉纤维发育中的功能机制，二者协同构成转录后调控网络。miRNA通过靶向切割或翻译抑制调控纤维起始与伸长，如miR156?SPL模块；lncRNA借助竞争性内源RNA（ceRNA）网络参与激素信号转导和脂肪酸代谢调控；siRNA源自反向重复转录本，可抑制纤维伸长；RNA结合蛋白（如PPR蛋白）通过调控线粒体RNA剪接影响纤维细胞能量代谢。目前研究已构建多层级调控框架，但功能验证深度不足，跨层级协同机制尚不清晰。未来需结合基因编辑、单细胞组学等技术解析动态网络，为纤维品质分子改良提供理论依据。
Abstract
Cotton fiber development serves as an ideal model for studying plant single-cell growth, and its high spatiotemporal precision depends on post-transcriptional regulation. This paper systematically reviews the functional mechanisms of non-coding RNA (miRNA, lncRNA, siRNA) and RNA-binding proteins in cotton fiber development, synergistically constitute a post-transcriptional regulatory network. miRNA regulate fiber initiation and elongation through target mRNA cleavage or translational repression, as exemplified by the miR156-SPL module. lncRNA participate in hormone signal transduction and fatty acid metabolism via competing endogenous RNA (ceRNA) networks. siRNA, derived from inverted repeat transcripts, can inhibit fiber elongation. RNA-binding proteins (e.g., PPR proteins) affect fiber cell energy metabolism by regulating mitochondrial RNA splicing. To date, a multi-layered regulatory framework has been established; however, functional validation remains insufficient, and cross-layer coordination mechanisms are still poorly understood. Future efforts should integrate gene editing, single-cell omics, and other advanced technologies to dissect the dynamic regulatory network, thereby providing a theoretical basis for the molecular improvement of fiber quality.关键词
棉花纤维/miRNA/lncRNA/siRNA/RNA结合蛋白Key words
cotton fiber/miRNA/lncRNA/siRNA/RNA-binding protein引用本文复制引用
张硕,谷淇深,孙正文,张冬梅,张艳,马峙英,王省芬.非编码RNA及RNA结合蛋白在棉花纤维发育中的功能研究进展[EB/OL].(2026-05-15)[2026-05-18].http://www.paper.edu.cn/releasepaper/content/202605-82.学科分类
生物科学研究方法、生物科学研究技术/分子生物学
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