Sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Abstract We enrolled 53 consecutive in-patients with COVID-19 at six hospitals in Toronto, Canada, and tested one nasopharyngeal swab/saliva sample pair from each patient for SARS-CoV-2. Overall, sensitivity was 89% for nasopharyngeal swabs and 77% for saliva (p=NS); difference in sensitivity was greatest for sample pairs collected later in illness.
Crowl Gloria、Coomes Eric、Powis Jeff、Liu Angel Xin、Anceva-Sami Sofia、Barati Shiva、Paterson Aimee、Khan Saman、Prost Karren、Poutanen Susan、McGeer Allison J.、Mozafarihashjin Mohammad、for the Toronto Invasive Bacterial Diseases Network COVID-19 Investigators、Farooqi Lubna、Jamal Alainna J.、Zhong Zoe、Yip Lily、Faheem Amna、Mubareka Samira
Sinai Health SystemFaculty of Medicine, University of TorontoMichael Garron HospitalSinai Health SystemSinai Health SystemSinai Health SystemSinai Health SystemSinai Health SystemSunnybrook Health Sciences CentreSinai Health System||Faculty of Medicine, University of TorontoInstitute of Health Policy, Management and Evaluation, University of Toronto||Sinai Health System||Faculty of Medicine, University of TorontoSinai Health SystemSinai Health SystemInstitute of Health Policy, Management and Evaluation, University of Toronto||Sinai Health System||Faculty of Medicine, University of TorontoSinai Health SystemSunnybrook Health Sciences CentreSinai Health SystemFaculty of Medicine, University of Toronto||Sunnybrook Health Sciences Centre
医学研究方法耳鼻咽喉科学
COVID-19SARS-CoV-2nasopharyngeal swabsaliva
Crowl Gloria,Coomes Eric,Powis Jeff,Liu Angel Xin,Anceva-Sami Sofia,Barati Shiva,Paterson Aimee,Khan Saman,Prost Karren,Poutanen Susan,McGeer Allison J.,Mozafarihashjin Mohammad,for the Toronto Invasive Bacterial Diseases Network COVID-19 Investigators,Farooqi Lubna,Jamal Alainna J.,Zhong Zoe,Yip Lily,Faheem Amna,Mubareka Samira.Sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)[EB/OL].(2025-03-28)[2025-08-02].https://www.medrxiv.org/content/10.1101/2020.05.01.20081026.点此复制
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