中枢神经轴突再生的细胞内信号转导机制研究进展

It was the main reason that Axon couldn't effectively regenerate after the injury of central nervous system, but the factors influencing central nervous system axonal regeneration was very complex, the regulating function of intracellular signal transduction might be the core mechanism. Recent studies indicated that Rho / ROCK and the cAMP-PKA signal transduction pathway was very important in regulating the axon regeneration，so the paper expounded the function of Rho / ROCK and the cAMP-PKA signal transduction in the process of axonal regeneration in order to provide the new treatment clue for the disease of central nervous system injury and neurodegenerative diseases.