预防老年抑郁症复发的最佳证据总结

Background The recurrence rate of senile depression is high, but there is a lack of research on prevention of senile depression at home and abroad. In the early stage, the research group explored the risk factors of senile depression recurrence, and the controllable risk factors were poor medication compliance, less activity, and less eating. Objective To search, evaluate and summarize evidence for prevention of depression recurrence in the elderly based on the above three risk factors. Methods The relevant evidences of geriatric depression and geriatric diseases associated with depression were searched from Web of Science, Pubmed, Cochrane Library, USA Guide.com, British Guidebook, Website of Ontario Nursing Association (RNAO), Evidence-based Nursing Center of Fudan University, CNKI and other databases.Including guidelines,system evaluation, expert consensus, evidence summary, etc. The retrieval period from database construction to October 2021. The quality and evidence level were evaluated by researchers trained in evidence-based medicine systems. Results A total of 15 literatures were included, including 3 guidelines, 11 systematic reviews and 1 RCT. The overall quality of literatures was high. A total of 24 best evidences were collected from six aspects: pre-intervention assessment, diet and nutrition,exercise and rehabilitation training, social psychological intervention, medication compliance, and effect evaluation. Conclusion This study summarized the best evidence of prevention of senile depression relapse, patients with clinical medical staff should be comprehensive assessment, and combine the characteristics of the patients and diseases, about diet and nutrition, exercise and rehabilitation training, medication compliance guidance, social psychological intervention such as setting individualized intervention plan.