乙酸半胱氨酸功能化聚硅氧烷的合成及组装
he Synthesis And Assemble of Acetylcysteine Functionalized Poly(methyl vinyl siloxane)
设计合成了基于聚甲基乙基硅氧烷为主连，通过巯烯反应利用乙酰半胱氨酸修饰聚硅氧烷。在中性和微酸性的体外水相环境中，初步测试了乙酰半胱氨酸功能化聚硅氧烷作为药物缓释载体对就尿啼唆药物的缓释作用，并得到了优异的结果。
In our work, we design and synthesis a drug deliver carrier material by thiol-ene reaction. The backbone is poly(methyl vinyl siloxane), modified by acetylcysteine. In buffer solution of different pH, we conducted different test on drug delivery and obtained good results.
张之达、郑富元、张洁
药学生物化学高分子化合物工业
聚硅氧烷功能化巯烯反应药物缓释
Polysiloxanesfunctionalizationthiol-ene reactiondrug sustained release
张之达,郑富元,张洁.乙酸半胱氨酸功能化聚硅氧烷的合成及组装[EB/OL].(2014-01-20)[2025-08-18].http://www.paper.edu.cn/releasepaper/content/201401-875.点此复制
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