微波辅助离子液体测定环境中残留红霉素的研究

s a kind of green solvent ionic liquids have attracted more and more interests, but there are few studies on microwave-assisted ionic liquids extraction. This paper treats hydrophobic ionic liquids [Bmim]PF6 as the object and under the condition of microwave radiation, investigates factors which will influent the extracting rate of erythromycin in different systems. The optimum technical conditions have been found by orthogonal experiment and it is: the temperature is 303.15k; the pH is 6 to 7; the microwave radiation power is 210w; the way is intermittent radiation (3 times and each lasts for 20s). The dosage of hydrophobic ionic liquids ([Bmim]PF6 is 3g and the extraction rate are 90.7%. Meanwhile, the analytic method of erythromycin in milk by microwave-assisted ionic liquids extraction was established. For the proposed method, the detection limit of 4 μg/kg, linear range of 5~50 μg/L, relative standard deviation of 1.7 were achieved.